Implementation of the laboratory diagnosis of fastidious growth microorganisms for Special Chemical-biological Programmes
Provider: Ministerstvo školství, mládeže a tělovýchovy
Programme: FRVŠ - B a)
Implementation period: 01.01.13 - 31.12.13
Workplace:
Description:
The aim of this project is implementation of new diagnostics methods for the detection of the growth-fastidious microorganisms, namely Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma urealyticum and Ureaplasma parvum, for the teaching of the students at the special chemical-biological fields. Mycoplasmas are the smallest free-living microorganisms. Mycoplasmal infections are commonly diagnosed by culture. However, culture is costly in that it requires special media enriched horse serum and yeast extract. Mycoplasmas are potentially pathogenic microorganisms that are frequently isolated from the urogenital tract of both men and women. These bacterial agents cause inflammation of the mucous membranes. In newborns, they can cause pneumonia, meningitis or abscesses. It has also been implicated in the extragenital infections, especially in immunocompromised patients. In the recent time their negative effect on human reproduction which is currently the subject of many studies has been reported. Molecular biological methods are highly sensitive, reliable, in comparison with the culture method. These facts suggest that the implementation of these methods in practical training of students may be a prerequisite for the expansion of the diagnostic mycoplasmal infections.
The aim of this project is implementation of new diagnostics methods for the detection of the growth-fastidious microorganisms, namely Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma urealyticum and Ureaplasma parvum, for the teaching of the students at the special chemical-biological fields. Mycoplasmas are the smallest free-living microorganisms. Mycoplasmal infections are commonly diagnosed by culture. However, culture is costly in that it requires special media enriched horse serum and yeast extract. Mycoplasmas are potentially pathogenic microorganisms that are frequently isolated from the urogenital tract of both men and women. These bacterial agents cause inflammation of the mucous membranes. In newborns, they can cause pneumonia, meningitis or abscesses. It has also been implicated in the extragenital infections, especially in immunocompromised patients. In the recent time their negative effect on human reproduction which is currently the subject of many studies has been reported. Molecular biological methods are highly sensitive, reliable, in comparison with the culture method. These facts suggest that the implementation of these methods in practical training of students may be a prerequisite for the expansion of the diagnostic mycoplasmal infections.
