New wound dressings with programmed release of active substances for biofilm inhibition.
Provider: Technologická agentura České republiky
Programme: Progresivní technologie, materiály a systémy (počátek řešení 2013)
Implementation period: 01.01.13 - 31.12.15
Workplace:
Fakulta chemicko-technologická - Katedra analytické chemie
Investigator: Metelka Radovan
Description:
This project, based on primary research and marketing studies, suggests a comprehensive proposal for research and development of new systems for an efficient inhibition of wound pathogens biofilm, that is gentle for patients. The project will be based on the principle of biofilm inhibition by programmed release of iodine using time-dependent generation of iodine from iodide by an oxidative agents (e.g., iodate, photochemically produced by reactive forms of oxygen, organic peroxides) and by using the release control with the help of iodine-binding polymer matrix. Also the benefit of inhibition of bacterial quorum sensing communication on the system will be tested during the project. The project covers research and development of wound dressings for the purpose of production specific products in the field of medical devices with improved properties over existing products, including the development of verified technology of their production.
This project, based on primary research and marketing studies, suggests a comprehensive proposal for research and development of new systems for an efficient inhibition of wound pathogens biofilm, that is gentle for patients. The project will be based on the principle of biofilm inhibition by programmed release of iodine using time-dependent generation of iodine from iodide by an oxidative agents (e.g., iodate, photochemically produced by reactive forms of oxygen, organic peroxides) and by using the release control with the help of iodine-binding polymer matrix. Also the benefit of inhibition of bacterial quorum sensing communication on the system will be tested during the project. The project covers research and development of wound dressings for the purpose of production specific products in the field of medical devices with improved properties over existing products, including the development of verified technology of their production.
