Determination of branched-chain amino acids (valine, leucine, isoleucine) and aromatic amino acids (phenylalanine, tyrosine) in dried blood spot for diagnosis of some diseases
Provider: Ministerstvo školství, mládeže a tělovýchovy
Programme: Interní rozvojová soutěž
Implementation period: 01.01.16 - 31.12.16
Workplace:
Fakulta chemicko-technologická - Katedra biologických a biochemických věd
Investigator: Kanďár Roman
Description:
The proposed project will enable the improvement of Clinical Biochemistry education within the degree course ?Analysis of Biological Materials? and ?Bioanalytic?. The newly established laboratory exercise exposes students to current clinical laboratory practice. Dried blood spot (DBS) technique has found use in newborn screening for congenital metabolic disease. Currently there is great interest in simple and non-invasive methods of blood sample collection. DBS technique meets these requirements; moreover, advantages of DBS sampling, compared to conventional blood collection, include minimal volume requirements (microliters), ease of transport to laboratory, ease of sample storage and stability of measured analytes.
The proposed project will enable the improvement of Clinical Biochemistry education within the degree course ?Analysis of Biological Materials? and ?Bioanalytic?. The newly established laboratory exercise exposes students to current clinical laboratory practice. Dried blood spot (DBS) technique has found use in newborn screening for congenital metabolic disease. Currently there is great interest in simple and non-invasive methods of blood sample collection. DBS technique meets these requirements; moreover, advantages of DBS sampling, compared to conventional blood collection, include minimal volume requirements (microliters), ease of transport to laboratory, ease of sample storage and stability of measured analytes.
