Proof of Concept of the Technology for Acetaminophen Toxicity Moderation
Provider: Technologická agentura České republiky
Programme: Program aplikovaného výzkumu, experimentálního vývoje a inovací GAMA
Implementation period: 01.01.16 - 31.12.17
Workplace:
Fakulta chemicko-technologická - Katedra biologických a biochemických věd
Investigator: Roušar Tomáš
Description:
The aim of the project is proof of concept of the technology for development of a new combined drug with paracetamol. This new pharmaceutical product will possess lower toxicity in comparison with other products. The use of standard pharma-product containing paracetamol can lead to the toxicity in liver and kidney after overdose. Based on our mostly unpublished and unique results, the main aim of present project is to prove our hypothesis on possible defense against this toxicity. The outcome of our project will be: 1) development of a new combined drug product containing paracetamol with lower toxicity 2) followed by commercialization.
The aim of the project is proof of concept of the technology for development of a new combined drug with paracetamol. This new pharmaceutical product will possess lower toxicity in comparison with other products. The use of standard pharma-product containing paracetamol can lead to the toxicity in liver and kidney after overdose. Based on our mostly unpublished and unique results, the main aim of present project is to prove our hypothesis on possible defense against this toxicity. The outcome of our project will be: 1) development of a new combined drug product containing paracetamol with lower toxicity 2) followed by commercialization.
