Modification of technologically important oligo/polyols by sophisticated esterification
Provider: Technologická agentura České republiky
Programme: Program aplikovaného výzkumu, experimentálního vývoje a inovací GAMA
Implementation period: 01.01.18 - 31.12.19
Workplace:
Fakulta chemicko-technologická - Katedra obecné a anorganické chemie
Investigator: Růžička Aleš
Description:
The project deals with the modification of several classes of compounds characteristic by the presence of one or more OH groups - such as vitamins A-D, taxols, prostaglandins, carbohydrates, cyclodextrins, polysacharides and lignin that are wholly or partly converted into esters. This modification will be made using a unique technology developed and improved at parent workplace, esterification of lactide in an inert solvent or dispersion to lactates or lactyllactate. Altered properties of the thus prepared products such as higher solubility, bioavailability, lipophilicity and biodegradability of these predicted to be useful in human medicine, such as food supplements, cosmetics, hygiene products etc.
The project deals with the modification of several classes of compounds characteristic by the presence of one or more OH groups - such as vitamins A-D, taxols, prostaglandins, carbohydrates, cyclodextrins, polysacharides and lignin that are wholly or partly converted into esters. This modification will be made using a unique technology developed and improved at parent workplace, esterification of lactide in an inert solvent or dispersion to lactates or lactyllactate. Altered properties of the thus prepared products such as higher solubility, bioavailability, lipophilicity and biodegradability of these predicted to be useful in human medicine, such as food supplements, cosmetics, hygiene products etc.
