Publication detail

Use of C,N-chelated di-n-butyltin(IV) fluoride for the synthesis of acyl fluorides, fluoroformates and fluorophosgene

Year: 2008

Type of publication: článek v odborném periodiku

Name of source: Tetrahedron Letters

Publisher name: Pergamon-Elsevier Science Ltd.

Place: Oxford

Page from-to: 6320-6323

Titles:

Language	Name	Abstract	Keywords
cze	Use of C,N-chelated di-n-butyltin(IV) fluoride for the synthesis of acyl fluorides, fluoroformates and fluorophosgene	{2-[(CH3)(2)NCH2]C6H4}(n-Bu)(2)SnF (1) reacts with various chloroformates, acyl chlorides, methanesulfonyl chloride, 4,4'-dimethoxytrityl chloride and phosgene precursors or derivatives to form fluorinated analogues. All reactions proceed rapidly and under mild conditions. The use of a catalytic amount of 1 and KF in toluene led to a relatively high yield of a selected fluoroformate. (C) 2008 Elsevier Ltd. All rights reserved.
eng	Use of C,N-chelated di-n-butyltin(IV) fluoride for the synthesis of acyl fluorides, fluoroformates and fluorophosgene	{2-[(CH3)(2)NCH2]C6H4}(n-Bu)(2)SnF (1) reacts with various chloroformates, acyl chlorides, methanesulfonyl chloride, 4,4'-dimethoxytrityl chloride and phosgene precursors or derivatives to form fluorinated analogues. All reactions proceed rapidly and under mild conditions. The use of a catalytic amount of 1 and KF in toluene led to a relatively high yield of a selected fluoroformate. (C) 2008 Elsevier Ltd. All rights reserved.	FLUORINATING AGENTS; HALIDES; TRIORGANOTIN(IV); REAGENT; LIGAND; ION

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