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Antioxidant Vitamin Pool in Senior Population
Authors: Mužáková Vladimíra | Roušar Tomáš | Žáková Pavla | Kanďár Roman | Vojtíšek Petr | Skalický Jiří
Year: 2003
Type of publication: ostatní - přednáška nebo poster
Name of source: Sborník abstrakt z 8. mezioborové česko-slovenské toxikologické konference
Publisher name: Česká lékařská společnost JEP
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Language Name Abstract Keywords
cze Hladiny antioxidačních vitamínů u starší populace antioxidant vitamins; senior patients; myocardial infarction; diabetes mellitus
eng Antioxidant Vitamin Pool in Senior Population Aim: To compare plasma concentration of alpha-tocopherol and ascorbic acid in healthy seniors (age over 65 years), senior patients with either diabetes mellitus, acute myocardial infarction or dyslipidemia and recommended values of these vitamins. Methods: Studied groups included 30 patients with diabetes mellitus (DM); 30 patients 1 ? 2 weeks after acute myocardial infarction (AMI); 11 patients with lipid metabolism disorder (LD, total cholesterol > 6.2 mM); and control group of 27 healthy persons. Results: Concentration of alpha-tocopherol in DM group was 14.6 +- 5.3 microM, in AMI group 13.7 +- 5.6 microM, in LD group 15.9 +- 5.6 microM and in control group 12.9 +- 4.1 microM. No statistically significant differences were found. However, comparison of determined values with levels recommended for prevention revealed remarkable shortage of alpha-tocopherol in the Czech population. Plasma concentration of ascorbic acid in DM group was 47.07 +- 22.80 microM, in AMI group 33.15 +- 12.81 microM, in LD group 45.59 +- 23.02 microM and in control group 43.28 +- 26.57 microM. No statistically significant differences were found between the controls and individual groups of patients. Plasma concentrations of vitamin C reached the recommended value in all cases except the AMI group, where it was significantly lower. Conclusion: Seniors in the Czech population were proved to be in highly significant shortage of -tocopherol, minor shortage of vitamin C was found only in group of patients with myocardial infarction. antioxidant vitamins; senior patients; myocardial infarction; diabetes mellitus

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