Publication detail

UHPLC/MS/MS Analysis of Anthelmintic Drugs and Their Metabolites

Authors: Jedličková Veronika | Jirásko Robert | Holčapek Michal | Skálová Lenka

Year: 2010

Type of publication: ostatní - přednáška nebo poster

Page from-to: nestránkováno

Titles:

Language	Name	Abstract	Keywords
cze	UHPLC/MS/MS Analysis of Anthelmintic Drugs and Their Metabolites	In our study, selected parasites are cultivated in flasks with a medium enriched by praziquantel (or ivermectin) and subsequently analyzed using UHPLC/MS/MS with the electrospray ionization. Both ESI polarity modes are used to obtain complementary information. The emphasis is given on the right calibration of the mass scale to achieve the high mass accuracy, which results in the elemental composition determination of ions observed in full-scan and tandem mass spectra. Moreover, advanced software tools are used for the prediction and identification of eventual metabolites.	UHPLC/MS/MS; anthelmintic drugs;metabolites

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