Publication detail

PLASMA LEVELS OF BETA-CAROTENE ARE INVERSELY CORRELATED TO INTERLEUKIN-6 IN PATIENTS WITH ADVANCED CORONARY ARTERY DISEASE

Authors: Mužáková Vladimíra | Skalický Jiří | Kanďár Roman | Meloun Milan | Vojtíšek Petr

Year: 2010

Type of publication: ostatní - přednáška nebo poster

Page from-to: nestránkováno

Titles:

Language	Name	Abstract	Keywords
eng	PLASMA LEVELS OF BETA-CAROTENE ARE INVERSELY CORRELATED TO INTERLEUKIN-6 IN PATIENTS WITH ADVANCED CORONARY ARTERY DISEASE	We investigated the interrelationships between plasma beta-carotene, alpha-tocopherol, and the level of systemic inflammation and oxidative stress in patients with advanced coronary artery disease (CAD). Parameters were determined in a group of patients with advanced coronary artery disease (S, n=91) and control group of patients with normal arteries (C, n=49). In patients with coronary stenosis (S) lower levels of beta-carotene (BC) and alpha-tocopherol (AT) coincided with higher level of inflammation. Advanced CAD coincided with significantly lower plasma concentrations of HDL-cholesterol and beta-carotene as well as with elevated levels of all inflammatory markers, but only mild increase of oxidative stress. Beta-carotene inversely correlated with interleukin-6, this could suggest potential protective effect of beta-carotene on atherosclerosis due to the inhibition of inflammatory processes.	BETA-CAROTENE; INTERLEUKIN-6; CORONARY ARTERY DISEASE

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