Login for students

Login for employees

Publication detail

The thermodynamic dissociation constants of naphazoline by the regression analysis of potentiometric data
Authors: Meloun Milan | Ferenčíková Zuzana | Netolická Lucie | Vrána Aleš
Year: 2011
Type of publication: článek v odborném periodiku
Name of source: Central European Journal of Chemistry
Publisher name: Springer
Page from-to: 66-74
Titles:
Language Name Abstract Keywords
cze Termodynamické disociační konstanty nafazolinu regresní analýzou potenciometrických dat Smíšená disociační konstanta nafazolinu byla upřena při různých iontových silách 0.1-0.26 a při teplotě 25 a 37C regresní analýzou úptenciometrických dat programy ESAb a HYPERQUAD. Vedle společných parametrů pK byly odhadovány i skupinové parametry L0 a HT. Termodynamická disociační konstanta byla určena nelineární regresí dat (pKa,I) při obou teplotách. potenciometrická titrace;disociační konstanty;nafazolin;ESAB;HYPERQUAD
eng The thermodynamic dissociation constants of naphazoline by the regression analysis of potentiometric data The mixed dissociation constant of naphazoline is determined at various ionic strengths I [mol dm-3] in the range of 0.01 to 0.26 and at temperatures of 25°C and 37°C using ESAB and HYPERQUAD regression analysis of the potentiometric titration data. A strategy of efficient experimentation is proposed in a protonation constant determination, followed by a computational strategy for the chemical model with a protonation constant determination. Two group parameters, L0 and HT were ill-conditioned in the model and their determination is therefore uncertain. These group parameters, L0 and HT, can significantly influence a systematic error in the estimated common parameter pKa and they always should be refined together with pKa. The thermodynamic dissociation constant pKTa was estimated by nonlinear regression of {pKa, I} data at 25°C and 37°C: for naphazoline pKTa1 = 10.41(1) and 10.13(2). potentiometric titration;dissociation constant;naphazoline;ESAB;HYPERQUAD

Departments

Other Parts

Map

en.mapy.cz

Services

Popular Links

© 2023 University of Pardubice, Studentská 95, 532 10 Pardubice 2
Phone: +420 466 036 111, 466 036 112, 466 036 113
Webmaster, RSS
Data box ID: f5vj9hu
Accessibility Statement
CC BY-NC-ND 4.0Creative CommonsAttributionNonCommercialNoDerivatives