Publication detail

In vitro studies of anthelmintik drugs

Year: 2011

Type of publication: ostatní - přednáška nebo poster

Page from-to: nestránkováno

Titles:

Language	Name	Abstract	Keywords
eng	In vitro studies of anthelmintik drugs	In this work, in vitro studies of anthelminthic drug ivermectin were performed. Rat hepatic cells and rat or parasitic mitochondrial fractions were used as biological models for incubations with the drug. The solid-phase extraction method was optimized for incubation mixtures. Extracted samples were subsequently analysed by UHPLC/MS/MS with the emphasis to detect and identify phase I and II metabolites of ivermectin.	ivermectin;UHPLC/MS/MS;drug metabolites

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