Publication detail

Biofunctionalization of different materials, e.g. nanofibers, micro- or nanoparticles, and its application in diagnostics and medicine.

Authors: Slováková Marcela

Year: 2013

Type of publication: ostatní - přednáška nebo poster

Page from-to: nestránkováno

Titles:

Language	Name	Abstract	Keywords
eng	Biofunctionalization of different materials, e.g. nanofibers, micro- or nanoparticles, and its application in diagnostics and medicine.	In the paper the immobilization strategy, carriers as nanofibers and spheric particles are described. Developed reactors were applied for specific detection or isolation of different targets, e.g. antibodies, disease markers, peptides; specific digestion by selected proteases, e.g. trypsin, proteinase K, papain, Arg-C (Clostripain), Lys-C; and phosphorylation by kinases. Methods of protein grafting are preferably covalent, due to advantageous attributes. In some cases a special covalent methods were used, so called oriented immobilizations, for ensuring the accessible orientation of a biomolecule active site. Development and applications of these reactors were intended for diagnostic, biotechnology and medicinal research.	Biofunctionalization; nanofibers; micro-; nanoparticles; diagnostics; medicine.

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