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Publication detail

How to use polarized ethylenes to syntheses of interesting heterocyclic compounds?
Authors: Brož Břetislav | Padělková Zdeňka | Šimůnek Petr
Year: 2013
Type of publication: ostatní - přednáška nebo poster
Page from-to: nestránkováno
Titles:
Language Name Abstract Keywords
eng How to use polarized ethylenes to syntheses of interesting heterocyclic compounds? This work is aimed to explore synthetic applications of some ?push-pull? polarized ethylenes for building various heterocyclic rings. The work follows previous methods and brings improved techniques for the preparation of the heterocyclic compounds with both electron-accepting and electron-withdrawing substituents. Some new polysubstituted 1H-pyrazolcarboxylic acid methyl esters have been successfully prepared in moderate yields. The reaction leading to fused tricyclic N-containing heterocycles is now investigated. It is expected that those derivatives could have an anti-bacterial or anti inflammatory effects. polarized ethylenes; synthesis; heterocycles