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In vitro antimicrobial activities of cinnamon bark oil, anethole, carvacrol, eugenol and guaiazulene against Mycoplasma hominis clinical isolates
Authors: Sleha Radek | Mosio Petra | Vydržalová Markéta | Jantovská Alexandra | Boštíková Vanda | Mazurová Jaroslava
Year: 2014
Type of publication: článek v odborném periodiku
Name of source: Biomedical Papers
Publisher name: Univerzita Palackého v Olomouci
Place: Olomouc
Page from-to: 208-2011
Titles:
Language Name Abstract Keywords
cze In vitro antimikrobiální aktivita skořicového oleje, anetholu, karvakrolu, eugenolu a guaiazulenu na kmeny Mycoplasma hominis Cílem této studie bylo ověřit antimikrobiální účinky pěti přírodních látek na 50 kmenů Mycoplasma hominis, izolovaných z klinického materiálu. antimikrobiální aktivita; skořicového oleje; anetholu; karvakrolu; eugenolu; guaiazulenu; Mycoplasma hominis
eng In vitro antimicrobial activities of cinnamon bark oil, anethole, carvacrol, eugenol and guaiazulene against Mycoplasma hominis clinical isolates Aims. The aim of this study was to evaluate the antimicrobial effects of five natural substances against 50 clinical isolates of Mycoplasma hominis. Methods and Results. The in vitro activity of selected natural compounds, cinnamon bark oil, anethole, carvacrol, eugenol and guaiazulene, was investigated against 50 M. hominis isolates cultivated from cervical swabs by the broth dilution method. All showed valuable antimicrobial activity against the tested isolates. Oil from the bark of Cinnamomum zeylanicum (MBC90 = 500 ?g/mL) however was found to be the most effective. Carvacrol (MBC90 = 600 ?g/mL) and eugenol (MBC90 = 1000 ?g/mL) also possessed strong antimycoplasmal activity. Conclusions. The results indicate that cinnamon bark oil, carvacrol and eugenol have strong antimycoplasmal activity and the potential for use as antimicrobial agents in the treatment of mycoplasmal infections. antimicrobial activities; cinnamon bark oil; anethole; carvacrol; eugenol; guaiazulene; Mycoplasma hominis; clinical isolates