Skip to main content

Login for students

Login for employees

Publication detail

Synthesis of ortho-condensed 1,4-dihydroquinoline based systems via Buchwald-Hartwig reaction
Authors: Brož Břetislav | Šimůnek Petr
Year: 2014
Type of publication: ostatní - přednáška nebo poster
Page from-to: nestránkováno
Titles:
Language Name Abstract Keywords
eng Synthesis of ortho-condensed 1,4-dihydroquinoline based systems via Buchwald-Hartwig reaction This work deals with the preparation of exo-cyclic “push-pull” polarized enaminoesters and their cyclization to the desired tricyclic derivatives via Buchwald-Hartwig cross coupling reaction. Using the new generation of Pd‑catalyst we found the procedure that allow the synthesis even the problematic seven-membered derivative in excellent yield. 1,4-dihydroquinoline; Buchwald-Hartwig reaction