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Publication detail

Effect of hypercrosslinking conditions on pore size distribution and efficiency of monolithic stationary phases
Authors: Urban Jiří | Škeříková Veronika
Year: 2014
Type of publication: článek v odborném periodiku
Name of source: Journal of Separation Science
Publisher name: Wiley-VCH
Place: Weinheim
Page from-to: 3082-3089
Titles:
Language Name Abstract Keywords
cze Vliv podmínek hypercroslinkování na velikost pórů a účinnost monolitikých stacionárních fází Tři různá halogenovaná rozpouštedla s různou délkou řetězce a tři různé "Friedel-Craftsovi katalyzátory" s různou reaktivitou byly použity pro přípravu vysoce zesítěných poly(styrene-co-vinylbenzyl chlorid-codivinylbenzen) kolon. Volba rozpouštědla a katalyzátoru ovlivňovala účinnost i hydronymamické vlastnosti připravovaných kolon. Účinnost; Hypercrosslinkování; Polymerní monolity; Distribude velikosti pórů; Malé molekuly
eng Effect of hypercrosslinking conditions on pore size distribution and efficiency of monolithic stationary phases Three dihalogenic solvents differing in the length of alkyl chain (1,2-dichloroethane, 1,4-dichlorobutane, and 1,6-dichlorohexane) with three Friedel-Crafts alkylation catalysts varying in reactivity (AlCl3, FeCl3, and SnCl4) have been used to prepare hypercrosslinked poly(styrene-co-vinylbenzyl chloride-co-divinylbenzene) columns. Hydrodynamic characteristics as well as column efficiency and mass transfer resistance were tuned by the combination of swelling solvent and alkylation reaction catalyst in the modification mixture. The column swelled in 1,6-dichlorohexane and hypercrosslinked in the presence of AlCl3 provided the highest column efficiency and enabled fast isocratic separations of small molecules in a RP mode. To uncover factors controlling the efficiency of hypercrosslinked monolithic columns, we have studied pore volume distribution of prepared columns. We found that column efficiency increases with the higher pore volume of pores smaller than 2 nm. Efficiency; Hypercrosslinking; Polymer monoliths; Pore size distribution; Small molecules