Login for students

Login for employees

Publication detail

Hypercrosslinking modification of organic polymer-based monoliths
Authors: Urban Jiří | Škeříková Veronika | Janků Simona | Hoznauerová Barbora
Year: 2014
Type of publication: článek ve sborníku
Name of source: 13th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-13) and 3rd International Symposium on Hyphenated Techniques for Sample Preparation (HTSP-3)
Publisher name: Royal Flemish Chemical Society (KVCV)
Place: Antwerp
Page from-to: 71-72
Titles:
Language Name Abstract Keywords
cze Modifikace povrchu organických polymerů vysokým zesítěním Hyperkroslinkování umožňuje připravit organické polymerní kapilární kolony vhodné pro rychlou a účinnou separaci malých molekul za izokratických podmínek. Účinnost kolony koresponduje s rozsahem zesítění a může být ovlivňována polaritou rozpouštědla, reaktivitou a polaritou alkylačního katalyzátoru a teplotou a časem modifikační reakce. Vysoké zesítění; organické monolity
eng Hypercrosslinking modification of organic polymer-based monoliths Hypercrosslinking post-polymerization modification allows preparation of organic polymer capillary monolithic columns suitable for fast and efficient separations of small molecules in isocratic liquid chromatography. Column efficiency corresponds to the extent of hypercrosslinking and can be tuned by several variables including polarity of the swelling solvent, reactivity and concentration of alkylation catalyst, and time and temperature of modification reaction. Three dihalogenic solvents differing in polarity (1,2-dichloroethane, 1,4-dichlorobutane, and 1,6-dichlorohexane) with three Friedel-Crafts alkylation catalysts varying in reactivity (AlCl3, FeCl3, and SnCl4) have been used to prepare hypercrosslinked poly(styrene-co-vinylbenzyl chloride-co-divinylbenzene) columns. After optimization of hypercrosslinking conditions including reaction time, temperature, and catalyst concentration, we prepared a column with efficiency exceeding 80 000 theoretical plates/m for benzene. Optimized hypercrosslinked columns enable fast separations at higher flow rates without the loss of efficiency as demonstrated by fast isocratic separation of low molecular compounds, such as barbiturates. We have also modified the surface of hypercrosslinked monoliths by zwitterionic monomer to prepare a column allowing a separation of polar compounds in hydrophilic interaction chromatography. The prepared column did not lose its separation power even after more than 10 000 injections which confirmed very high stability of the modification reaction. Finally, the optimized capillary monolithic column has been applied in comprehensive two-dimensional chromatography of polar phenolic acids and flavones. Hypercroslinking; organic monoliths

Departments

Other Parts

Map

en.mapy.cz

Services

Popular Links

© 2023 University of Pardubice, Studentská 95, 532 10 Pardubice 2
Phone: +420 466 036 111, 466 036 112, 466 036 113
Webmaster, RSS
Data box ID: f5vj9hu
Accessibility Statement
CC BY-NC-ND 4.0Creative CommonsAttributionNonCommercialNoDerivatives