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Electrochemical behavior and voltammetric determination of folates folic acid and leucovorin and antifolate methotrexate using bare boron-doped diamind electrode
Year: 2014
Type of publication: ostatní - článek ve sborníku
Name of source: 15th International Conference on Electroanalysis
Publisher name: Malmö University
Place: Malmö
Page from-to: 214
Titles:
Language Name Abstract Keywords
eng Electrochemical behavior and voltammetric determination of folates folic acid and leucovorin and antifolate methotrexate using bare boron-doped diamind electrode The possibility of application of bare boron-doped diamond electrode (BDDE) in voltammetric analysis of the folates folic acid and leucovorin and antifolate methotrexate has been investigated. Cyclic voltammetry and direct current voltammetry has been used for study of its voltammetric behavior. Differential pulse voltammetry has been applied for development of sensitive methods of determination for tested electroactive compounds. Various statistical parameters, e.g., relative standard deviations of repeated measurements or limits of detection, were calculated. The proposed methods were successfully applied for analysis of real samples of vitamin products and drugs. Boron-doped diamond electrode; Voltammetric analysis; Folic acid; Leucovorin; Methotrexate

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