Publication detail

Fast In-source CE/MS Separation of Biologically Active Compounds

Authors: Váňová Jana | Česla Petr | Píchová Klára | Nováková Zuzana | Fischer Jan

Year: 2015

Type of publication: ostatní - článek ve sborníku

Page from-to: nestránkováno

Titles:

Language	Name	Abstract	Keywords
eng	Fast In-source CE/MS Separation of Biologically Active Compounds	In this work, coupling of capillary zone electrophoresis (CZE) with mass spectrometry (MS) was used for the analysis of maltooligosaccharides and polyphenolic compounds. Both groups of analytes represent biologically active compounds with important role in human organism. Polyphenols can help protect a human body from influence of the free radicals and can improve an immune function and lower the risks of infection or cancer. Oligosaccharides play an important role in many cellular events as effective components of the information-carrier molecules family for the finely tunable role played in extra-cellular-signaling, recognition, trafficking, adhesion and proliferation phenomena. The developed CZE/MS coupling utilized coaxial sheath-flow interface and electrospray ionization (ESI). The possibilities of using in-source capillary for fast electrophoretic separation have been tested.

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