Publication detail

Investigation of the electrochemical behavior of mesalazine on boron-doped diamond electrode

Authors: Štěpánková Michaela | Šelešovská Renáta | Janíková Lenka | Chýlková Jaromíra

Year: 2016

Type of publication: článek ve sborníku

Name of source: XXXVI Moderní elektrochemické metody

Publisher name: BEST Servis

Place: Ústí nad Labem

Page from-to: 247-251

Titles:

Language	Name	Abstract	Keywords
cze	Studium voltametrického chování mesalazinu na borem dopované diamantové elektrodě	Bylo studováno voltametrické chování mesalazinu na borem dopované diamantové elektrodě a vyvinuta metoda jeho stanovení. Ta byla aplikována při analýze farmaceutického přípravku i biologických vzorků.	Borem dopovaná diamantová elektroda; voltametrie; mesalazin; stanovení
eng	Investigation of the electrochemical behavior of mesalazine on boron-doped diamond electrode	The possibility of application of boron-doped diamond electrode (BDDE) for voltammetric analysis of anti-inflammatory drug mesalazine has been investigated. Cyclic voltammetry was used for study of the voltammetric behavior of mesalazine depending on pH of supporting electrolyte and scan rate. It was found that it provides one oxidation peak on BDDE and the highest current response was observed in Britton-Robinson buffer of pH 7.0. Square wave voltammetry was applied for mesalazine determination and low limit of detection was reached 6.96×10−7 mol L−1. Finally, the proposed method has been successfully used in the analysis of the drug in commercial tablet form.	Boron-doped diamond electrode; Voltammetry; Mesalazine; Determination

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