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RENAL CELL LINES FOR STUDY OF NEPHROTOXICITY IN VITRO
Authors: Dastychová Eva | Hauschke Martina | Roušar Tomáš
Year: 2016
Type of publication: článek v odborném periodiku
Name of source: Vojenské zdravotnické listy
Page from-to: 69-74
Titles:
Language Name Abstract Keywords
cze Ledvinné buněčné kultury ke studiu nefrotoxicity Ledviny jsou orgánem, který je velmi často vystaven účinku toxinů díky metabolickému obratu, za jenž ledvinná tkán zodpovídá. Renální buněčné kultury; in vitro testy
eng RENAL CELL LINES FOR STUDY OF NEPHROTOXICITY IN VITRO The kidneys are one of the organ that can be commonly damaged by a number of toxic compounds (heavy metals, xenobiotics, drugs, etc.). To characterize the mechanism of toxicity, a variety of methods have been developed. The in vitro methods belong among the mostly used. Especially, the use of cell lines seems to be the leading approach to test and to characterize the toxicity mechanisms. Renal cell lines; in vitro tests