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The Influence of Polyhexamethylene Guanidine Derivatives Introduced into Polyhydroxybutyrate on Biofilm Formation and the Activity of Bacterial Enzymes
Authors: Brzezinska M. Swiontek | Walczak M. | Richert A. | Kalwasinska A. | Pejchalová Marcela
Year: 2016
Type of publication: článek v odborném periodiku
Name of source: Applied Biochemistry and Microbiology
Publisher name: MAIK Nauka/Interperiodica/Springer
Place: New York
Page from-to: 298-303
Titles:
Language Name Abstract Keywords
cze Vliv derivátů polyhexamethylen guanidinu zakomponovaných do Polyhydroxybutyrátu na tvorbu biofilmu a aktivitu bakteriálních enzymů publikace studuje vliv derivátů polyhexamethylen guanidinu zakomponovaných do polyhydroxybutyrátu na tvorbu biofilmu a aktivitu bakteriálních enzymů u bakterií E. coli a S. aureus. poyhyroxybutarát; biofilm; bakteriální enzymy
eng The Influence of Polyhexamethylene Guanidine Derivatives Introduced into Polyhydroxybutyrate on Biofilm Formation and the Activity of Bacterial Enzymes Escherichia coli and Staphylococcus aureus were able to produce biofilm on the surface of polyhydroxybutyrate (PHB), but their abundance depended on type and the concentrations of the polyhexamethylene guanidine (PHMG) derivatives introduced in PHB. Different types of PHMG derivatives inhibited S. aureus ATCC 6538P biofilm formation, but PHB with PHMG salt of sulfanilic acid stimulated E. coli ATCC 8739 biofilm formation. The presence of all PHMG derivatives decreased significantly the number of viable cells of the test bacteria directly proportional to the concentration of the biocidal agent. PHMG derivatives affected the activity of microbiological hydrolases with different degrees. Some of them (PHB with PHMG stearate) stimulated activity of E. coli ATCC 8739 hydrolases, other (PHB with the PHMG salt of sulfanilic acid) inhibited activity of the S. aureus ATCC 6538P hydrolases. The PHMG derivatives introduced in PHB also inhibited the activity of bacterial dehydrogenases polyhydroxybutyrate; biofilm; bacterial enzymes

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