Publication detail

Kinetic study of 1,3-dipolar cycloaddition of N-phenylsydnones with terminal alkynes

Authors: Hladíková Veronika | Hanusek Jiří

Year: 2016

Type of publication: ostatní - přednáška nebo poster

Page from-to: nestránkováno

Titles:

Language	Name	Abstract	Keywords
eng	Kinetic study of 1,3-dipolar cycloaddition of N-phenylsydnones with terminal alkynes	Pyrazoles belong to an interesting class of organic compounds with various chemical applications. The 1,3-dipolar cycloaddition reaction of sydnones with various dipolarophiles offers a convenient synthetic route for preparation of pyrazole derivatives. We performed preliminary HPLC kinetic study of Cu-mediated cycloaddition of N-phenylsydnones with terminal alkynes (CuSAC) giving exclusively 1,4-diarylpyrazoles. The reaction rate was measured under various conditions.

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