Publication detail

Borem dopované diamantové elektrody s různým obsahem boru – Stanovení leukovorinu

Year: 2017

Type of publication: článek ve sborníku

Name of source: XXXVII. Moderní elektrochemické metody : sborník přednášek

Publisher name: BEST Servis

Place: Ústí nad Labem

Page from-to: 201-205

Titles:

Language	Name	Abstract	Keywords
cze	Borem dopované diamantové elektrody s různým obsahem boru – Stanovení leukovorinu	Elektrochemické vlastnosti borem dopovaných diamantových elektrod s různým obsahem boru byly studovány pomocí cyklické voltametrie redoxních systémů ([Ru(NH3)6]3+/2+) a ([Fe(CN6)]4−/3−). Aplikační možnosti těchto elektrod elektrod byly testovány při stanovení leukovorinu.	Borem dopovaná diamantová elektroda; obsah boru; elektrochemické vlastnosti; leukovorin; stanovení
eng	Boron-doped diamond electrodes with different boron content – Determination of leucovorin	Electrochemical properties of boron-doped diamond electrodes (BDDEs) with different boron content were studied using cyclic voltammetry of inner-sphere ([Ru(NH3)6]3+/2+) and outer-sphere ([Fe(CN6)]4−/3−) redox markers. Their application possibilities in analysis of organic bioactive compounds were tested by determination of drug leucovorin in model solutions as well as in pharmaceutical preparations. Voltammetric behavior of leucovorin was studied and voltammetric method for its determination was developed using commercially available BDDE. This proposed method was applied for lab-made BDDEs and the appropriated statistical parameters (e.g., LDR, LOD, LOQ, and RSD) were calculated and compared with respect to the boron content.	Boron-doped diamond electrode; Boron content; Electrochemical properties; Leucovorin; Determination

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