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Sensing with Imidazole Push-Pull Molecules

Authors: Bureš Filip | Kulhánek Jiří | Dey Nilanjan | Santanu Bhattacharya

Year: 2021

Type of publication: ostatní - přednáška nebo poster

Page from-to: nestránkováno

Titles:

Language	Name	Abstract	Keywords
eng	Sensing with Imidazole Push-Pull Molecules	Nowadays, molecular detectors and sensors attract great attention due to their wide application potential. In general, an organic substance capable of detection/sensing should be easy-to-synthesize and possesses efficient and selective mechanism of sensing. In this respect, organic push-pull chromophores are very tempting examples as their optical properties are dictated by intramolecular charge-transfer (ICT). Moreover, the extent of the ICT is quite sensitive towards environment, which makes the sensing easily distinguishable by naked eye or by using simple and inexpensive equipment. In 2011, we have reported on (bi)imidazole push-pull derivatives and their application in nonlinear optics. Subsequently in 2019, these derivatives were investigated for simultaneous detection of Cu2+ and Hg2+ ions. Two independent sensing pathways were revealed. Trace level of both metal ions even in complex matrices as well as on-site detection using simple easy paper strips were achieved. Very recently, the aforementioned results on imidazole push-pull molecules were extended by their application as artificial enzyme for detection and detoxification of nerve gas agents. The selected imidazole derivative was able to detect and detoxify Sarin and Tabun mimic with the LOD of 35 and 45 ppb. The proposed mechanism involved production of phosphorylated intermediate, which underwent time-dependent hydrolysis accompanied by a release of the free probe (enzyme-like action). Moreover, these processes were accompanied by turning on/off imidazole emissive properties, which significantly facilitated the detection.	imizazole; push-pull molecules; gas detection; nerve gas