Publication detail

A new approach to determining the drug guaifenesin using voltammetric and flow injection analysis

Year: 2024

Type of publication: ostatní - článek ve sborníku

Name of source: 43rd Modern Electrochemical Methods :Proceedings of the International Conference

Publisher name: BEST Servis

Place: Ústí nad Labem

Page from-to: 96-100

Titles:

Language	Name	Abstract	Keywords
eng	A new approach to determining the drug guaifenesin using voltammetric and flow injection analysis	This study presents a new method for detecting guaifenesin (GFE) in pharmaceutical samples. We employed screen-printed sensors with a boron-doped diamond electrode (BDDE) to develop and validate both voltammetric and flow injection analysis with electrochemical detection (FIA-ED) methods. These approaches were effectively used to analyze model solutions, pharmaceutical preparations, and serum samples spiked with GFE, producing accurate results comparable to those obtained with HPLC/DAD analysis. The developed methods provide straightforward, sensitive, and selective means for determining GFE in various sample matrices, underscoring the potential of SP/BDDE in electrochemical analysis.	Guaifenesin, Screen-printed sensor, Boron-doped diamond electrode, Voltammetry, Flow-injection analysis, Pharmaceutical preparations.

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