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Combining hollow fiber microextraction with square wave voltammetry at screen-printed boron-doped diamond electrodes for the determination of trazodone in urine
Authors: Labzova Oleksandra | Hrdlička Vojtěch | Navrátil Tomáš | Šelešovská Renáta
Year: 2025
Type of publication: ostatní - článek ve sborníku
Name of source: 44th modern electrochemical methods : proceedings of the international conference
Publisher name: BEST Servis
Place: Ústí nad Labem
Page from-to: 97-100
Titles:
Language Name Abstract Keywords
eng Combining hollow fiber microextraction with square wave voltammetry at screen-printed boron-doped diamond electrodes for the determination of trazodone in urine A new hollow fiber-based liquid-phase microextraction (HF-LPME) method for the determination of antidepressant medication trazodone (TRZ) in biological samples was developed. HF-LPME was combined with optimized square wave voltammetry (SWV) on screen-printed boron-doped diamond electrode (SP-BDDE). Optimum HF-LPME conditions were: supported liquid membrane (SLM) isoamyl benzoate, 0.1 mol L−1 H2SO4 as acceptor solution, BRB (pH = 10) as donor phase, and time of extraction 35 min. Limits of quantification (LOQ) and detection (LOD) were 42 and 12 nmol L−1, respectively. The applicability of the developed method was verified on human urine. Trazodone, Hollow fiber liquid-phase microextraction, Screen-printed boron-doped diamond electrode, Square wave voltammetry