doc. Ing. Alena Komersová, Ph.D.
- alena.komersova@upce.cz
- 466 037 093
-
FChT Vice-Dean for External Relations (34000)
Faculty of Chemical Technology
vice-deanDepartment of Physical Chemistry (30340)Faculty of Chemical Technology
headassociate professor
- Teaching
- Publications
- Projects
Teaching
| KFCH/CA141 (2024) | G - - - | |
| KFCH/CD141 (2024) | G - - - | |
| KFCH/C062 (2024) | - PR - SE | |
| KFCH/C063 (2024) | - - CV - | |
| KFCH/C119 (2024) | G PR - SE | |
| KFCH/C228 (2024) | G PR - - | |
| KFCH/C309A (2024) | G - - - | |
| KFCH/C320 (2024) | G PR - SE | |
| KFCH/C432 (2024) | G - - - | |
| KFCH/C697 (2024) | G - - - | |
| KFCH/C908 (2024) | - PR - - |
Timetable
| 25. 11. 2024 | ||||
| 10:00-12:00 | HA / S6 | KFCH | C119 | 13 |
| 12:00-14:00 | HA / S6 | KFCH | C119 | 13 |
| 26. 11. 2024 | ||||
| 10:00-11:00 | HA / S16 | KFCH | C320 | 9 |
| 11:00-12:00 | HA / S16 | KFCH | C320 | 9 |
| 13:00-15:00 | HA / S11 | KFCH | C062 | 4 |
| 15:00-17:00 | HA / S11 | KFCH | C062 | 4 |
Dates
Publications
| SVOBODA, R. - NEVYHOŠTĚNÁ, M. - MACHÁČKOVÁ, J. - VACULÍK, J. - KNOTKOVÁ, K. - CHROMCIKOVA, M. - KOMERSOVÁ, A. Thermal degradation of Affinisol HPMC: Optimum Processing Temperatures for Hot Melt Extrusion and 3D Printing Pharmaceutical Research, 2023, vol. 40, no. 9, s. 2253-2268. ISSN: 0724-8741. | |
| SVOBODA, R. - KOUTNÁ, N. - KOŠŤÁLOVÁ, D. - KRBAL, M. - KOMERSOVÁ, A. Indomethacin: Effect of Diffusionless Crystal Growth on Thermal Stability during Long-Term Storage Molecules, 2023, vol. 28, no. 4, s. "1568-1"-"1568-22". ISSN: 1420-3049. | |
| MACHÁČKOVÁ, J. - NEVYHOŠTĚNÁ, M. - MATZICK, K. - KOMERSOVÁ, A. BIOPOLYMER FILAMENTS DESIGNED FOR FDM 3D PRINTING OF PERSONALISED ORALLY ADMINISTERED DOSAGE FORMS. In Proceedings of the 10th International Conference on Chemical Technology. Praha: AMCA, spol. s r.o., 2023. s. 174 s. ISBN 978-80-88307-18-1. | |
| SVOBODA, R. - KOŠŤÁLOVÁ, D. - KRBAL, M. - KOMERSOVÁ, A. Indomethacin: The Interplay between Structural Relaxation, Viscous Flow and Crystal Growth Molecules, 2022, vol. 27, no. 17, s. "5668-1"-"5668-23". ISSN: 1420-3049. | |
| KOMERSOVÁ, A. - SVOBODA, R. - SKALICKÁ, B. - BARTOŠ, M. - SNEJDROVA, E. - MUZIKOVA, J. - MATZICK, K. Matrix Tablets Based on Chitosan-Carrageenan Polyelectrolyte Complex: Unique Matrices for Drug Targeting in the Intestine Pharmaceuticals, 2022, vol. 15, no. 8, s. "980-1"-"980-25". ISSN: 1424-8247. | |
| SKALICKÁ, B. - MATZICK, K. - KOMERSOVÁ, A. - SVOBODA, R. - BARTOŠ, M. - HROMÁDKO, L. 3D-Printed Coating of Extended-Release Matrix Tablets: Effective Tool for Prevention of Alcohol-Induced Dose Dumping Effect Pharmaceutics, 2021, vol. 13, no. 12, s. "2123-1"-"2123-27". ISSN: 1999-4923. | |
| SKALICKÁ, B. - MATZICK, K. - KOMERSOVÁ, A. - LOCHAŘ, V. - BARTOŠ, M. - MUZIKOVA, J. - HADDOUCHI, S. A New Approach to the Dissolution Tests Management to Obtain Kinetic and Thermodynamic Data: Release of a Model Drug from Glyceryl Behenate Matrix Tablets European Journal of Lipid Science and Technology, 2021, vol. 123, no. 5, s. "2000235-1"-"2000235-8". ISSN: 1438-7697. | |
| MUSELIK, J. - KOMERSOVÁ, A. - KUBOVA, K. - MATZICK, K. - SKALICKÁ, B. A Critical Overview of FDA and EMA Statistical Methods to Compare In Vitro Drug Dissolution Profiles of Pharmaceutical Products Pharmaceutics, 2021, vol. 13, no. 10, s. "1703-1"-"1703-12". ISSN: 1999-4923. | |
| WEIDLICH, T. - KAMENICKÁ, B. - BENEŠ, L. - ČIČMANCOVÁ, V. - KOMERSOVÁ, A. - CERMAK, J. - ŠVEC, P. Cu-Catalyzed Hydrodehalogenation of Brominated Aromatic Pollutants in Aqueous Solution Catalysts, 2021, vol. 11, no. 6, s. 699. ISSN: 2073-4344. | |
| WEIDLICH, T. - KAMENICKÁ, B. - MELÁNOVÁ, K. - ČIČMANCOVÁ, V. - KOMERSOVÁ, A. - ČERMÁK, J. Hydrodechlorination of Different Chloroaromatic Compounds at Room Temperature and Ambient Pressure-Differences in Reactivity of Cu- and Ni-Based Al Alloys in an Alkaline Aqueous Solution Catalysts, 2020, vol. 10, no. 9, s. 994. ISSN: 2073-4344. | |
| SVOBODA, R. - ROMANOVÁ, J. - ŠLANG, S. - OBADALOVA, I. - KOMERSOVÁ, A. Influence of particle size and manufacturing conditions on the recrystallization of amorphous Enzalutamide European Journal of Pharmaceutical Sciences, 2020, vol. 153, no. October, s. "105468-1"-"105468-11". ISSN: 0928-0987. | |
| LOCHAŘ, V. - KOMERSOVÁ, A. - MATZICK, K. - SKALICKÁ, B. - BARTOŠ, M. - MUZIKOVA, J. - HADDOUCHI, S. The effect of alcohol on ionizing and non-ionizing drug release from hydrophilic, lipophilic and dual matrix tablets Saudi Pharmaceutical Journal, 2020, vol. 28, no. 2, s. 187-195. ISSN: 1319-0164. | |
| MUSELIK, J. - KOMERSOVÁ, A. - LOCHAŘ, V. - KUBOVA, K. Regresní analýza disolučního profilu léčiva a odhad mechanismu uvolňování léčiva Chemické listy, 2019, vol. 113, no. 5, s. 328-336. ISSN: 0009-2770. | |
| MATZICK, K. - SLEZÁKOVÁ, B. - LOCHAŘ, V. - KOMERSOVÁ, A. FTIR Study of the Interactions Between Alginate and Chitosan Biopolymers During Dissolution Process. In 7th International Conference on Chemical Technology : book of abstracts. Praha: Česká společnost průmyslové chemie, 2019. s. P54-P54 s. ISBN 978-80-88307-01-3. | |
| ROMANOVÁ, J. - KOMERSOVÁ, A. - SVOBODA, R. - PEKÁREK, T. Chemical Interactions in Solid State: Changes in Behaviour of Matrix Tablets Due to the Chemical Interactions of Individual Components. In 7th International Conference on Chemical Technology : book of abstracts. Praha: Česká společnost průmyslové chemie, 2019. s. PH8-PH8 s. ISBN 978-80-88307-01-3. | |
| SLEZÁKOVÁ, B. - MATZICK, K. - KOMERSOVÁ, A. - LOCHAŘ, V. The Effect of the Temperature on the Pentoxifylline Release from Lipophilic Matrix Tablets. In 7th International Conference on Chemical Technology : book of abstracts. Praha: Česká společnost průmyslové chemie, 2019. s. P51-P51 s. ISBN 978-80-88307-01-3. | |
| D'YACHENKO, A. - ROMANOVÁ, J. - KOMERSOVÁ, A. The influence of the lubricants on the dissolution kinetics of the matrix tablets. In Sborník příspěvků: studentská vědecká odborná činnost 2018/2019. Pardubice: Univerzita Pardubice, 2019. s. 21-26 s. ISBN 978-80-7560-260-2. | |
| MATZICK, K. - SLEZÁKOVÁ, B. - KOMERSOVÁ, A. - LOCHAŘ, V. RELEASE KINETICS OF TRAMADOL HYDROCHLORIDE FROM MATRICES CONTAINING MIXTURE OF BIOPOLYMERS – ALGINATE AND CHITOSANE. In 7th International Conference on Chemical Technology : book of abstracts. Praha: Česká společnost průmyslové chemie, 2019. s. PH7-PH7 s. ISBN 978-80-88307-01-3. | |
| KOMERSOVÁ, A. - KOVÁŘOVÁ, M. - KOMERS, K. - LOCHAŘ, V. - ČEGAN, A. Why is the hydrolytic activity of acetylcholinesterase pH dependent? Kinetic study of acetylcholine and acetylthiocholine hydrolysis catalyzed by acetylcholinesterase from electric eel Zeitschrift für Naturforschung C = A Journal of Biosciences, 2018, vol. 73, no. 9-10, s. 345-351. ISSN: 0939-5075. | |
| ROMANOVÁ, J. - SVOBODA, R. - OBADALOVA, I. - BENEŠ, L. - PEKAREK, T. - KREJCIK, L. - KOMERSOVÁ, A. Amorphous Enzalutamide - Non-isothermal recrystallization kinetics and thermal stability Thermochimica Acta, 2018, vol. 665, no. July, s. 134-141. ISSN: 0040-6031. | |
| KOMERSOVÁ, A. - LOCHAŘ, V. - MYSLÍKOVÁ, K. - MUŽÍKOVÁ, J. - BARTOŠ, M. The effect of co-processed dry binder with microcrystalline cellulose on release of verapamil hydrochloride from hydrophilic matrix tablets Acta Poloniae Pharmaceutica - Drug Research, 2018, vol. 75, no. 5, s. 1223-1231. ISSN: 0001-6837. | |
| MUZIKOVA, J. - KOMERSOVÁ, A. - LOCHAŘ, V. - VILDOVA, L. - VOŠOUSTOVÁ, B. - BARTOŠ, M. Comparative evaluation of the use of dry binders in a physical mixture or as a coprocessed dry binder in matrix tablets with extended drug release Acta Pharmaceutica, 2018, vol. 68, no. 3, s. 295-311. ISSN: 1330-0075. | |
| KOMERSOVÁ, A. - LOCHAŘ, V. - SLEZÁKOVÁ, B. - MUŽÍKOVÁ, J. EXTENDED RELEASE OF PENTOXIFYLLINE - DUAL MATRIX TABLETS CONTAINING POLYVINYL ALCOHOL AND GLYCERYL DIBEHENATE. In Book of abstracts of the 6th International Conference on Chemical Technology. Praha: Česká společnost průmyslové chemie, 2018. s. L7-L7 s. ISBN 978-80-86238-83-8. | |
| ROMANOVÁ, J. - SVOBODA, R. - KOMERSOVÁ, A. - PEKÁREK, T. Interaction between the API and excipients in solid state dosage form prepared by direct compression method. In 13th International Conference on Solid State Chemistry : book of abstracts. Pardubice: Univerzita Pardubice, 2018. s. 168-168 s. ISBN 978-80-7560-158-2. | |
| ROMANOVÁ, J. - SVOBODA, R. - OBADALOVÁ, I. - PEKÁREK, T. - KREJČÍK, L. - KOMERSOVÁ, A. Recrystallization kinetics of Enzalutamide with regard to processing, storage and handling conditions. In 13th International Conference on Solid State Chemistry : book of abstracts. Pardubice: Univerzita Pardubice, 2018. s. 114-114 s. ISBN 978-80-7560-158-2. | |
| LOCHAŘ, V. - KOMERSOVÁ, A. - MATZICK, K. Solubility of verapamil hydrochloride in aqueous solutions depending on temperature. In Book of abstracts of the 6th International Conference on Chemical Technology. Praha: Česká společnost průmyslové chemie, 2018. s. P80-P80 s. ISBN 978-80-86238-83-8. | |
| MYSLÍKOVÁ, K. - KOMERSOVÁ, A. - LOCHAŘ, V. - MUŽÍKOVÁ, J. Extended release tablets containing co-processed dry binders and tramadol hydrochloride - determination of the content uniformity Scientific Papers of the University of Pardubice, Series A, Faculty of Chemical Technology, 2017, vol. 23, no. květen, s. 115-128. ISSN: 1211-5541. | |
| MYSLÍKOVÁ, K. - KOMERSOVÁ, A. - LOCHAŘ, V. - MUŽÍKOVÁ, J. Effect of alcohol on tramadol hydrochloride release from controlled release formulations containing co-processed dry binders. In Proceedings of the 5th International Conference on Chemical Technology. Praha: Česká společnost průmyslové chemie, 2017. s. 433-438 s. ISBN 978-80-86238-65-4. | |
| MYSLÍKOVÁ, K. - KOMERSOVÁ, A. - LOCHAŘ, V. Release kinetics of tramadol hydrochloride from solid drug formulations Scientific Papers of the University of Pardubice, Series A, Faculty of Chemical Technology, 2016, vol. 22, no. květen 2016, s. 67-79. ISSN: 1211-5541. | |
| KOMERSOVÁ, A. - LOCHAŘ, V. - MYSLÍKOVÁ, K. - MUŽÍKOVÁ, J. - BARTOŠ, M. Formulation and dissolution kinetics study of hydrophilic matrix tablets with tramadol hydrochloride and different co-processed dry binders European Journal of Pharmaceutical Sciences, 2016, vol. 95, no. December, s. 36-45. ISSN: 0928-0987. | |
| MUŽÍKOVÁ, J. - HOLUBOVÁ, K. - KOMERSOVÁ, A. - LOCHAŘ, V. Study of dual matrix tablets containing hypromellose of different viscosity degree and glyceryl dibehenate Acta Poloniae Pharmaceutica, 2016, vol. 73, no. 2, s. 461-468. ISSN: 0001-6837. | |
| MYSLÍKOVÁ, K. - LOCHAŘ, V. - KOMERSOVÁ, A. - MUŽÍKOVÁ, J. Effect of Alcohol and Pepsine Presence to Dissolution from Hydrophilic Matrix Tablets. In Proceedings of the 4th International Conference on Chemical Technology. Praha: Česká společnost průmyslové chemie, 2016. s. P66-P66 s. ISBN 978-80-86238-94-4. | |
| MUŽÍKOVÁ, J. - MUCHOVÁ, S. - KOMERSOVÁ, A. - LOCHAŘ, V. Compressibility of tableting materials and properties of tablets with glyceryl behenate Acta Pharmaceutica, 2015, vol. 65, no. 1, s. 91-98. ISSN: 1330-0075. | |
| MUŽÍKOVÁ, J. - HÁVOVÁ, S. - ONDREJČEK, P. - KOMERSOVÁ, A. - LOCHAŘ, V. A study of tablets with a co-processed dry binder containing hypromellose and alpha-lactose monohydrate Journal of Drug Delivery Science and Technology, 2014, vol. 24, no. 1, s. 100-104. ISSN: 1773-2247. | |
| SOUKUPOVÁ, L. - KOMERSOVÁ, A. - KOMERS, K. - ŠTĚPÁNKOVÁ, Š. - ČEGAN, A. Kinetic of the Total Hydrolysis of Acetyl-β-methylcholine by Acetylcholinesterase Reaction Kinetics and Catalysis Letters, 2008, vol. 95, no. 2, s. 205-211. ISSN: 0133-1736. | |
| KOMERSOVÁ, A. - MASOPUSTOVÁ, M. - KOMERS, K. - ŠTĚPÁNKOVÁ, Š. - ČEGAN, A. In vitro Inhibition of Cholinesterases by Carbamates ? A Kinetic Study Zeitschrift fuer Naturforschung C-A Journal of Biosciences, 2007, vol. 62c, no. N, s. 305-307. ISSN: 0939-5075. | |
| ŠTĚPÁNKOVÁ, Š. - KOMERS, K. - KOMERSOVÁ, A. - MASOPUSTOVÁ, M. - ČEGAN, A. Inhibition of Cholinesterases by Dialkylcarbamates Zeitschrift fuer Naturforschung C-A Journal of Biosciences, 2007, vol. 62c, no. N, s. 308-310. ISSN: 0939-5075. | |
| KOMERSOVÁ, A. - KOMERS, K. - ČEGAN, A. New Findings about Ellman´s Method to Determine Cholinesterase Activity Zeitschrift fuer Naturforschung C-A Journal of Biosciences, 2007, vol. 62c, no. N, s. 150-154. ISSN: 0939-5075. | |
| ŠTĚPÁNKOVÁ, Š. - KOMERS, K. - KOMERSOVÁ, A. - ČEGAN, A. Stanovení kinetických konstant neinhibovaných a inhibovaných hydrolýz acetylcholinu. In ChemZi. Bratislava: Slovenská chemická spoločnosť pri SAV, 2007. s. 79-80 s. | |
| ZDRAŽILOVÁ, P. - ŠTĚPÁNKOVÁ, Š. - KOMERSOVÁ, A. - VRÁNOVÁ, M. - KOMERS, K. - ČEGAN, A. Kinetics of 13 new cholinesterase inhibitors Zeitschrift fuer Naturforschung C-A Journal of Biosciences, 2006, vol. 61c, no. 7-8, s. 611-617. ISSN: 0939-5075. | |
| ZDRAŽILOVÁ, P. - ŠTĚPÁNKOVÁ, Š. - VRÁNOVÁ, M. - KOMERS, K. - KOMERSOVÁ, A. - ČEGAN, A. Kinetics of total enzymatic hydrolysis of acetylcholine and acetylthiocholine Zeitschrift fuer Naturforschung C-A Journal of Biosciences, 2006, vol. 61c, no. 3-4, s. 289-294. ISSN: 0939-5075. | |
| ŠTĚPÁNKOVÁ, Š. - ČEGAN, A. - KOMERS, K. - KOMERSOVÁ, A. - MASOPUSTOVÁ, M. Kinetics of uninhibited and inhibited hydrolysis of acetylcholine and acetylthiocholine. In International Congress of Young Chemists "YoungChem 2006". Warsaw University of Technology: Chemical Scientific Society "Flogiston", 2006. s. 134 s. ISBN N. | |
| MASOPUSTOVÁ, M. - KOMERSOVÁ, A. - ŠTĚPÁNKOVÁ, Š. - KOMERS, K. Kinetics of Cholinesterases Inhibition by New Carbamates. In YoungChem2006, book of abstracts. Warsaw: Chemical Scietific Society Flogiston, 2006. s. 114-114 s. ISBN nemá. | |
| KOMERSOVÁ, A. - KOMERS, K. - ZDRAŽILOVÁ, P. Kinetics of Hydrolysis of Acetylthiocholine and Acetylcholine by Cholinesterases. Chemico-biological Interactions, 2005, vol. N, no. 157-158, s. 387-388. ISSN: 0009-2797. | |
| ŠTĚPÁNKOVÁ, Š. - VRÁNOVÁ, M. - ZDRAŽILOVÁ, P. - KOMERS, K. - KOMERSOVÁ, A. - ČEGAN, A. Two New Methods Monitoring Kinetics of Hydrolysis of Acetylcholine and Acetylthiocholine Zeitschrift fuer Naturforschung C-A Journal of Biosciences, 2005, vol. 60c, no. 11-12, s. 943-946. ISSN: 0939-5075. | |
| ZDRAŽILOVÁ, P. - KOMERS, K. - ŠTĚPÁNKOVÁ, Š. - KOMERSOVÁ, A. Kinetics of Hydrolysis of Acetylthiocholine by Cholinesterases.. In European Congress of Young Chemists, Youngchem 2004. Varšava: Warsaw University of Technology, 2004. s. 111 s. ISBN N. | |
| KOMERS, K. - KOMERSOVÁ, A. - STRATILOVÁ, J. Comment on Colorimetric Monitoring of Enzymatic Hydrolysis of Acetylthiocholine Scientific Papers of the University of Pardubice, Series A, Faculty of Chemical Technology, 2003, vol. N, no. 9, s. 89-97. ISSN: 1211-5541. |
Projects
Study and application of new materials for chemical and pharmaceutical technologies
01.01.24 - 31.12.24
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
01.01.24 - 31.12.24
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
Basic research and applications of perspective materials for chemical and pharmaceutical technologies
01.01.22 - 31.12.22
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
01.01.22 - 31.12.22
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
Study of new materials for chemical and pharmaceutical technologies and other applications
01.01.21 - 31.12.21
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
01.01.21 - 31.12.21
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
Research of prospective materials for chemical and pharmaceutical technology and other applications
01.01.20 - 31.12.20
Programme: Student Grant Competition
Funded by:
Position on the project: Principal Investigator
01.01.20 - 31.12.20
Programme: Student Grant Competition
Funded by:
Position on the project: Principal Investigator
Special materials for chemical and pharmaceutical technology and other applications
01.01.19 - 31.12.19
Programme: Student Grant Competition
Funded by:
Position on the project: Principal Investigator
01.01.19 - 31.12.19
Programme: Student Grant Competition
Funded by:
Position on the project: Principal Investigator
Tablets preparation using 3D printing
01.01.19 - 30.11.19
Programme: Internal development competition
Funded by:
Position on the project: Principal Investigator
01.01.19 - 30.11.19
Programme: Internal development competition
Funded by:
Position on the project: Principal Investigator
Study of advanced materials for chemical technology and other applications
01.01.18 - 31.12.18
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
01.01.18 - 31.12.18
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
Study of new materials for chemical technology and other applications
01.01.17 - 31.12.17
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
01.01.17 - 31.12.17
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
Synthesis and characterisation of advanced materials for chemical technology and other applications
01.01.16 - 31.12.16
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
01.01.16 - 31.12.16
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
New materials for chemical technology and another applications
01.01.15 - 31.12.15
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
01.01.15 - 31.12.15
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
New Materials for Chemical Technologies and Other Applications
01.01.14 - 31.12.14
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
01.01.14 - 31.12.14
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
