Ing. Karel Pauk, Ph.D.
- karel.pauk@upce.cz
-
Institute of Organic Chemistry and Technology (30320)
Faculty of Chemical Technology
researcher -
- Professional profile
- Publications
- Projects
Education and academic qualifications
Rok
2007
Obor
Chemistry and technical chemistry
Škola
University of Pardubice
Název práce
Anhydrides of aromatic di- and tetra- carboxylic acids in organic synthesis of polycyclic pigments
Rok
2009
Obor
Organic technology
Škola
University of Pardubice
Název práce
Synthesis and conditioning of the Pigment Red 188
Rok
2014
Obor
Organic chemistry
Škola
Iniversity of Pardubice
Název práce
Synthesis and biological activity of N - aryl / alkyl - salicylamide and their precursors
Job overview
Od (rok)
2014
Zastávaná pozice
Scientific researcher
Zaměstnavatel
University of Pardubice
Publications
| PAUK, K. - LUŇÁK, S. - MACHALICKÝ, O. - PERDIH, F. - VYŇUCHAL, J. - ELIÁŠ, Z. - IMRAMOVSKÝ, A. Four Slip-Stacked Arrangements, Three Types of Photophysics: Crystal Structure and Solid-State Fluorescence of 3,6-Diaryl Substituted Furo[3,4-c]furanone Polymorphs and Regioisomers ChemPlusChem, 2023, vol. 88, no. 8, s. e202300310. ISSN: 2192-6506. | |
| KRATOCHVÍL, M. - THOTTAPPALI, M. - LUŇÁK, S. - PAUK, K. - RAIS, D. - MARKOVÁ, A. - PFLEGER, J. - IMRAMOVSKÝ, A. - VALA, M. Solid-State Absorption, Luminescence, and Singlet Fission of Furanyl-Substituted Diketopyrrolopyrroles with Different π-Stacking Arrangements ChemPhotoChem, 2023, vol. 7, no. 12, s. e202300201. ISSN: 2367-0932. | |
| PINDJAKOVA, D. - PILAŘOVÁ, E. - PAUK, K. - MICHNOVÁ, H. - HOSEK, J. - MAGAR, P. - CIZEK, A. - IMRAMOVSKÝ, A. - JAMPILEK, J. Study of Biological Activities and ADMET-Related Properties of Salicylanilide-Based Peptidomimetics International Journal of Molecular Sciences, 2022, vol. 23, no. 19, s. 11648. ISSN: 1661-6596. | |
| PAUK, K. - LUŇÁK, S. - RŮŽIČKA, A. - MARKOVÁ, A. - TEICHMANOVÁ, K. - MAUSOVÁ, A. - KRATOCHVÍL, M. - SMOLKA, R. - MIKYSEK, T. - WEITER, M. - IMRAMOVSKÝ, A. - VALA, M. Colour-tuneable solid-state fluorescence of crystalline powders formed from push–pull substituted 2,5-diphenyl-stilbenes RSC Advances, 2022, vol. 12, no. 54, s. 34797–34807. ISSN: 2046-2069. | |
| PILAŘOVÁ, E. - JORDA, R. - SVOBODOVÁ, K. - PAUK, K. - KRYŠTOF, V. - IMRAMOVSKÝ, A. Synthesis and antiproliferative activity of the salicyl-based Weinreb amides and their derivatives in cancer cell lines. Scientific Papers of the University of Pardubice, Series A, Faculty of Chemical Technology, 2022, vol. 28, no. May 23, 2022, s. 127-149. ISSN: 1211-5541. | |
| STRAIHORODSKA, L. - PAUK, K. - IMRAMOVSKÝ, A. Synthesis and characterization of substituted diphenylamine distyrylstilbenes. In Sborník příspěvků: studentská vědecká odborná činnost 2021/2022. Pardubice: Univerzita Pardubice, 2022. s. 191–196 s. ISBN 978-80-7560-434-7. | |
| MAGAR, P. - PARRAVICINI, O. - ŠTĚPÁNKOVÁ, Š. - SVRČKOVÁ, K. - GARRO, A. - JENDRZEJEWSKA, I. - PAUK, K. - HOSEK, J. - JAMPILEK, J. - ENRIZ, R. - IMRAMOVSKÝ, A. Novel Sulfonamide-Based Carbamates as Selective Inhibitors of BChE International Journal of Molecular Sciences, 2021, vol. 22, no. 17, s. 9447. ISSN: 1661-6596. | |
| JORDA, R. - MOLITOROVÁ, V. - PILAŘOVÁ, E. - VOJÁČKOVÁ, V. - ŘEZNÍČKOVÁ, E. - SVOBODOVÁ, K. - PAUK, K. - IMRAMOVSKÝ, A. - KRYŠTOF, V. Pseudopeptides with aldehyde or vinylsulfone warheads: Synthesis and antiproteasomal activity Bioorganic Chemistry, 2021, vol. 115, no. October, s. 105228. ISSN: 0045-2068. | |
| PAUK, K. - LUŇÁK, S. - RŮŽIČKA, A. - MARKOVÁ, A. - MAUSOVÁ, A. - KRATOCHVÍL, M. - MELÁNOVÁ, K. - WEITER, M. - IMRAMOVSKÝ, A. - VALA, M. Green, red and infrared emitting polymorphs of sterically hindered push-pull substituted stilbenes Chemistry - A European Journal, 2021, vol. 27, no. 13, s. 4341–4348. ISSN: 0947-6539. | |
| RAIS, D. - TOMAN, P. - PFLEGER, J. - ACHARYA, U. - PANTHI, Y. - MENSIK, M. - ZHIGUNOV, A. - THOTTAPPALI, M. - VALA, M. - MARKOVA, A. - STRITESKY, S. - WEITER, M. - CIGANEK, M. - KRAJCOVIC, J. - PAUK, K. - IMRAMOVSKÝ, A. - ZAYKOV, A. - MICHL, J. Singlet Fission in Thin Solid Films of Bis(thienyl)diketopyrrolopyrroles ChemPlusChem, 2020, vol. 85, no. 12, s. 2689-2703. ISSN: 2192-6506. | |
| JORDA, R. - MAGAR, P. - HENDRYCHOVA, D. - PAUK, K. - DIBUS, M. - PILAŘOVÁ, E. - IMRAMOVSKÝ, A. - KRYSTOF, V. Novel modified leucine and phenylalanine dipeptides modulate viability and attachment of cancer cells European Journal of Medicinal Chemistry, 2020, vol. 188, no. February, s. "112036-1"-"112036-13". ISSN: 0223-5234. | |
| AGOSTINHO MONTEIRO, S. - IMRAMOVSKÝ, A. - PAUK, K. - RŮŽIČKOVÁ, Z. - CARVALHO, C. - PAVLIK, J. Synthesis of Alfaprostol Key Intermediate Ynol via Br/Mg Exchange Organic preparations and procedures international, 2020, vol. 52, no. 2, s. 127-138. ISSN: 0030-4948. | |
| POSPISILOVA, S. - MICHNOVA, H. - KAUEROVA, T. - PAUK, K. - KOLLAR, P. - VINSOVA, J. - IMRAMOVSKÝ, A. - CIZEK, A. - JAMPILEK, J. In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci Bioorganic & Medicinal Chemistry Letters, 2018, vol. 28, no. 12, s. 2184-2188. ISSN: 0960-894X. | |
| IMRAMOVSKÝ, A. - PAUK, K. - PAVLÍK, J. Optimalizace vybraných stupňů výroby Corey Alkoholu-A (-) – aplikace jednotlivých optimalizovaných stupňů do celkové výroby Corey Alkoholu-A (-). CZ: Univerzita Pardubice. | |
| ŠIMON, V. - IMRAMOVSKÝ, A. - PAUK, K. Corey alkohol-A(-) – chirální meziprodukt organické syntézy. In Sborník příspěvků : studentská vědecká odborná činnost 2017/2018. Pardubice: Univerzita Pardubice, 2018. s. 163-168 s. ISBN 978-80-7560-157-5. | |
| DUŠEK, J. - IMRAMOVSKÝ, A. - PAUK, K. - JORDA, R. - ŘEZNICKOVA, E. - KRYŠTOF, V. Synthesis and Antiproliferative Activities of Novel O-Benzyl Salicylamide Derivatives LETTERS IN DRUG DESIGN & DISCOVERY, 2017, vol. 14, no. 6, s. 662-671. ISSN: 1570-1808. | |
| JORDA, R. - DUŠEK, J. - ŘEZNÍČKOVÁ, E. - PAUK, K. - MAGAR, P. - IMRAMOVSKÝ, A. - KRYŠTOF, V. Synthesis and proteasomal activity of novel O-benzyl salicylamide-based inhibitors built from leucine and phenylalanine European Journal of Medicinal Chemistry, 2017, vol. 135, no. July, s. 142-158. ISSN: 0223-5234. | |
| AGOSTINHO MONTEIRO, S. - IMRAMOVSKÝ, A. - PAUK, K. - PAVLÍK, J. Novel synthetic approach to alfaprostol key intermediates via Stille coupling with an alkyne Tetrahedron Letters, 2017, vol. 58, no. 23, s. 2228-2231. ISSN: 0040-4039. | |
| IMRAMOVSKÝ, A. - PAUK, K. - PAVLÍK, J. Optimalizace výrobního stupně Mono acetát-A (-) – meziproduktu výroby Corey alkoholu.. CZ: Univerzita Pardubice. | |
| IMRAMOVSKÝ, A. - PAUK, K. - PAVLÍK, J. Optimalizace výrobního stupně Corey acetát-A(-) – meziproduktu výroby Corey alkoholu.. CZ: Univerzita Pardubice. | |
| IMRAMOVSKÝ, A. - PAUK, K. - PAVLÍK, J. Optimalizace výrobního stupně Chlorketoacetát-A – meziproduktu výroby Corey alkoholu.. CZ: Univerzita Pardubice. | |
| KUSHKEVYCH, I. - KOLLAR, P. - FERREIRA, A. - PALMA, D. - DUARTE, A. - LOPES, M. - BARTOS, M. - PAUK, K. - IMRAMOVSKÝ, A. - JAMPILEK, J. Antimicrobial effect of salicylamide derivatives against intestinal sulfate-reducing bacteria Journal of Applied Biomedicine, 2016, vol. 14, no. 2, s. 125-130. ISSN: 1214-021X. | |
| IMRAMOVSKÝ, A. - PAUK, K. - PAVLÍK, J. Technologie přípravy a výroby alfa řetězce nehalogenovaného prostaglandinového analogu alfaprostolu. CZ: Univerzita Pardubice, Cayman Pharma s.r.o. Neratovice. | |
| ZADRAŽILOVÁ, I. - POSPÍŠILOVÁ, S. - PAUK, K. - IMRAMOVSKÝ, A. - VINŠOVÁ, J. - ČÍŽEK, A. - JAMPÍLEK, J. In Vitro Bactericidal Activity of 4-and 5-Chloro-2-hydroxy-N-[1-oxo-1-(phenylamino)alkan-2-yl]benzamides against MRSA Biomed Research International, 2015, vol. 2015, no. říjen, s. "349534-1"-"349534-8". ISSN: 2314-6133. | |
| IMRAMOVSKÝ, A. - PAUK, K. - ELIÁŠ, Z. - PAVLÍK, J. Technologie přípravy a výroby omega řetězce alfaprostolu. CZ: Univerzita Pardubice, Cayman Pharma s.r.o. Neratovice. | |
| PAUK, K. - ZADRAŽILOVÁ, I. - IMRAMOVSKÝ, A. - VINŠOVÁ, J. - POKORNÁ, M. - MASAŘÍKOVÁ, M. - ČÍŽEK, A. - JAMPÍLEK, J. New derivatives of salicylamides: Preparation and antimicrobial activity against various bacterial species Bioorganic & Medicinal Chemistry, 2013, vol. 21, no. 21, s. 6574-6581. ISSN: 0968-0896. | |
| IMRAMOVSKÝ, A. - ŠTĚPÁNKOVÁ, Š. - VANČO, J. - PAUK, K. - MONREAL-FERRIZ, J. - VINŠOVÁ, J. - JAMPILEK, J. Acetylcholinesterase-Inhibiting Activity of Salicylanilide N-Alkylcarbamates and Their Molecular Docking Molecules, 2012, vol. 17, no. 9, s. 10142-10158. ISSN: 1420-3049. | |
| IMRAMOVSKÝ, A. - PAUK, K. - PADĚLKOVÁ, Z. - HANUSEK, J. Crystal Structure of the 5-Chloro Salicylamides: Three Different Types of the H-bonding Influenced Linear Chain Formation in the Solid State. Crystals, 2012, vol. 2, no. 2, s. 349-361. ISSN: 2073-4352. | |
| IMRAMOVSKÝ, A. - PAUK, K. - PEJCHAL, V. - HANUSEK, J. Salicylanilides and Their Derivates as Perspective Anti-tuberculosis Drugs: Synthetic Routes and Biological Evaluations Mini-reviews in Organic Chemistry, 2011, vol. 8, no. 2, s. 211-220. ISSN: 1570-193X. | |
| IMRAMOVSKÝ, A. - FÉRRIZ, J. - PAUK, K. - KRÁTKÝ, M. - VINŠOVÁ, J. Synthetic Route for the Preparation of 2-Hydroxy-N-[1-(2-hydroxyphenylamino)1-oxoalkan-2-yl]benzamides Journal of Combinatorial Chemistry, 2010, vol. 12, no. 4, s. 414-416. ISSN: 1520-4766. |
Projects
Near-infrared emitting molecular crystals for next generation imaging (Crystal-NIR)
01.01.24 - 31.12.26
Programme: Standard projects
Funded by:
Position on the project: Co-Investigator
01.01.24 - 31.12.26
Programme: Standard projects
Funded by:
Position on the project: Co-Investigator
Pseudopeptide proteasome inhibitors
01.01.18 - 31.12.20
Programme: Standard projects
Funded by:
Position on the project: Co-Investigator
01.01.18 - 31.12.20
Programme: Standard projects
Funded by:
Position on the project: Co-Investigator
Multi-photon absorbing Materials FOR 3D fabrication and 3D imaging (M-FOR-3D)
01.01.17 - 31.12.19
Programme: Standard projects
Funded by:
Position on the project: Co-Investigator
01.01.17 - 31.12.19
Programme: Standard projects
Funded by:
Position on the project: Co-Investigator
Optimizing the synthesis of Corey Alcohol-A (-), input material for the production of human and veterinary drugs
01.01.16 - 31.12.17
Programme: Programme of applied research, experimental development and innovations GAMA
Funded by:
Position on the project: Co-Investigator
01.01.16 - 31.12.17
Programme: Programme of applied research, experimental development and innovations GAMA
Funded by:
Position on the project: Co-Investigator
Development of technology for non-halogenated veterinary prostaglandins and their intermediates.
01.01.13 - 31.12.16
Programme: Progressive technology, materials and systems (starting in 2013)
Funded by:
Position on the project: Co-Investigator
01.01.13 - 31.12.16
Programme: Progressive technology, materials and systems (starting in 2013)
Funded by:
Position on the project: Co-Investigator
