RNDr. Jiří Handl, Ph.D.
- jiri.handl@upce.cz
- 466 037 699, 466 037 717
-
Department of Biological and Biochemical Sciences (30440)
Faculty of Chemical Technology
assistant professor
- Teaching
- Publications
Teaching
| FCH/U3V (2023) | - PR - - | |
| KBBV/C311 (2023) | G PR - - | |
| KBBV/C368 (2023) | - - CV - | |
| KBBV/C374 (2023) | G - CV - | |
| KBBV/C428 (2023) | G - - - | |
| KBBV/C429 (2023) | G - - - | |
| KBBV/C434 (2023) | G - - - | |
| KBBV/C441 (2023) | G - CV - | |
| KBBV/C466 (2023) | - PR - - | |
| KBBV/C472 (2023) | - PR - SE | |
| KBBV/C473 (2023) | - - CV - | |
| KBBV/C482 (2023) | G - CV - | |
| KBBV/C484 (2023) | G - - - | |
| KBBV/C485 (2023) | G - CV - | |
| KBBV/C540 (2023) | - - CV - | |
| KBBV/C556 (2023) | G - CV - | |
| KBBV/C873 (2023) | G - - - |
Timetable
Dates
Publications
| BENEK, O. - VASKOVA, M. - MISKERIKOVA, M. - SCHMIDT, M. - ANDRYS, R. - ROTTEROVA, A. - SKARKA, A. - HATLAPATKOVA, J. - ZDAROVA KARASOVA, J. - MEDVECKY, M. - HROCH, L. - VINKLAROVA, L. - FISAR, Z. - HROUDOVA, J. - HANDL, J. - ČAPEK, J. - ROUŠAR, T. - KOBRLOVA, T. - DOLEZAL, R. - SOUKUP, O. - AITKEN, L. - GUNN-MOORE, F. - MUSILEK, K. Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation European Journal of Medicinal Chemistry, 2023, vol. 258, no. October, s. 115593. ISSN: 0223-5234. | |
| SVOBODOVA, B. - PULKRABKOVA, L. - PANEK, D. - MISIACHNA, A. - KOLCHEVA, M. - ANDRYS, R. - HANDL, J. - ČAPEK, J. - NÝVLTOVÁ, P. - ROUŠAR, T. - PRCHAL, L. - HEPNAROVA, V. - HRABINOVA, M. - MUCKOVA, L. - TOSNEROVA, D. - KARABANOVICH, G. - FINGER, V. - SOUKUP, O. - HORAK, M. - KORABECNY, J. Structure-Guided Design of N-Methylpropargylamino- Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease International Journal of Molecular Sciences, 2023, vol. 24, no. 11, s. 9124. ISSN: 1661-6596. | |
| ROUŠAR, T. - HANDL, J. - ČAPEK, J. - NÝVLTOVÁ, P. - ROUŠAROVÁ, E. - KUBÁT, M. - ŠMÍD, L. - VÁŇOVÁ, J. - MALINAK, D. - MUSILEK, K. - ČESLA, P. Cysteine conjugates of acetaminophen and p-aminophenol are potent inducers of cellular impairment in human proximal tubular kidney HK-2 cells Archives of Toxicology, 2023, vol. 97, no. 11, s. 2943-2954. ISSN: 0340-5761. | |
| BÁČOVÁ, J. - KNOTEK, P. - KOPECKÁ, K. - HROMÁDKO, L. - ČAPEK, J. - NÝVLTOVÁ, P. - BRŮČKOVÁ, L. - SCHROTEROVA, L. - SESTAKOVA, B. - PALARČÍK, J. - MOTOLA, M. - CIZKOVA, D. - BEZROUK, A. - HANDL, J. - FIALA, Z. - RUDOLF, E. - BÍLKOVÁ, Z. - MACÁK, J. - ROUŠAR, T. Evaluating the Use of TiO2 Nanoparticles for Toxicity Testing in Pulmonary A549 Cells International Journal of Nanomedicine, 2022, vol. 17, no. 2022, s. 4211-4225. ISSN: 1178-2013. | |
| HANDL, J. - NÝVLTOVÁ, P. - ČAPEK, J. - ČESLA, P. - HOVSEPYAN, A. - AVETISYAN, S. - MIČÁNKOVÁ, P. - BRŮČKOVÁ, L. - STAŇKOVÁ, P. - KNOTKOVÁ, K. - PETROSYAN, T. - ROUŠAR, T. The comparison of biological effects of bacterial and synthetic melanins in neuroblastoma cells Food and Chemical Toxicology, 2022, vol. 168, no. October, s. 113355. ISSN: 0278-6915. | |
| HANDL, J. - NÝVLTOVÁ, P. - ČAPEK, J. - ROUŠAR, T. Differences in the biological effects of bacterial and synthetic melanin. In Military Medical Science Letters. Brno: Univerzita obrany v Brně, 2022. | |
| TICHÁ, L. - ČAPEK, J. - ROUŠAR, T. - HANDL, J. Charakterizace toxicity vybraných těžkých kovů s využitím moderních bioanalytických metod. In Sborník příspěvků: studentská vědecká odborná činnost 2021/2022. Pardubice: Univerzita Pardubice, 2022. s. 215-221 s. ISBN 978-80-7560-434-7. | |
| ČAPEK, J. - HANDL, J. - NÝVLTOVÁ, P. - ROUŠAR, T. Studying cadmium neurotoxicity in vitro. In Military Medical Science Letters. Brno: Univerzita obrany v Brně, 2022. | |
| HANDL, J. - MALINAK, D. - ČAPEK, J. - ANDRYS, R. - ROUŠAROVÁ, E. - HAUSCHKE, M. - BRŮČKOVÁ, L. - ČESLA, P. - ROUŠAR, T. - MUSILEK, K. Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening Chemical Research in Toxicology, 2021, vol. 34, no. 3, s. 699-703. ISSN: 0893-228X. | |
| MAJTNEROVÁ, P. - ČAPEK, J. - PETIRA, F. - HANDL, J. - ROUŠAR, T. Quantitative spectrofluorometric assay detecting nuclear condensation and fragmentation in intact cells Scientific Reports, 2021, vol. 11, no. 1, s. 11921. ISSN: 2045-2322. | |
| MEZEIOVA, E. - JANOCKOVA, J. - ANDRYS, R. - SOUKUP, O. - KOBRLOVA, T. - MUCKOVA, L. - PEJCHAL, J. - SIMUNKOVA, M. - HANDL, J. - MIČÁNKOVÁ, P. - ČAPEK, J. - ROUŠAR, T. - HRABINOVA, M. - NEPOVIMOVA, E. - LUIS MARCO-CONTELLES, J. - VALKO, M. - KORABECNY, J. 2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease European Journal of Medicinal Chemistry, 2021, vol. 211, no. February, s. 113112. ISSN: 0223-5234. | |
| MOTOLA, M. - ČAPEK, J. - ZAZPE, R. - BÁČOVÁ, J. - HROMÁDKO, L. - BRŮČKOVÁ, L. - NG, S. - HANDL, J. - SPOTZ, Z. - KNOTEK, P. - BAISHYA, K. - MAJTNEROVÁ, P. - PŘIKRYL, J. - SOPHA, H. - ROUŠAR, T. - MACÁK, J. Thin TiO2 Coatings by ALD Enhance the Cell Growth on TiO2 Nanotubular and Flat Substrates ACS Applied Bio Materials, 2020, vol. 3, no. 9, s. 6447-6456. ISSN: 2576-6422. | |
| NOVÁKOVÁ, G. - DRABINA, P. - BRŮČKOVÁ, L. - BÁČOVÁ, J. - HANDL, J. - SVOBODA, J. - VRBICKÝ, M. - ROUŠAR, T. - SEDLÁK, M. Enantioselective Synthesis of Clavaminol A, Xestoaminol C and their Stereoisomers Exhibiting Cytotoxic Activity European Journal of Organic Chemistry, 2020, vol. 2020, no. 24, s. 3671-3679. ISSN: 1434-193X. | |
| HANDL, J. - ČAPEK, J. - MAJTNEROVÁ, P. - BÁČOVÁ, J. - ROUŠAR, T. The Effect of Repeated Passaging on the Susceptibility of Human Proximal Tubular HK 2 Cells to Toxic Compounds Physiological Research, 2020, vol. 69, no. 4, s. 731-738. ISSN: 0862-8408. | |
| HANDL, J. - ČAPEK, J. - MAJTNEROVÁ, P. - PETIRA, F. - HAUSCHKE, M. - ROUŠAROVÁ, E. - ROUŠAR, T. Transient Increase in Cellular Dehydrogenase Activity After Cadmium Treatment Precedes Enhanced Production of Reactive Oxygen Species in Human Proximal Tubular Kidney Cells Physiological Research, 2019, vol. 68, no. 3, s. 481-490. ISSN: 0862-8408. | |
| HANDL, J. - ČAPEK, J. - BÁČOVÁ, J. - HROMÁDKO, L. - MACÁK, J. - ROUŠAR, T. Evaluation of the impact of TiO2 and SiO2 nanofibers on the neuronal cells.. In Toxicology Letters. vol. 314(S1) : abstracts of the 55th Congress of the European Societies of Toxicology (EUROTOX 2019). Kidlington: Elsevier, 2019. | |
| HANDL, J. - ČAPEK, J. - MAJTNEROVÁ, P. - BRŮČKOVÁ, L. - ROUŠAR, T. Hodnocení změn funkčního stavu lidských proximálních tubulárních buněk. In Bioimplantologie 2019. Brno: MSD, spol. s r.o., 2019. ISBN 978-80-7392-307-5. | |
| HANDL, J. - MELOUN, M. - NOVÁKOVÁ MUŽÁKOVÁ, V. Inflammatory markers in dependence on the plasma concentration of 37 fatty acids after the coronary stent implantation Journal of Pharmaceutical and Biomedical Analysis, 2018, vol. 149, no. February, s. 96-105. ISSN: 0731-7085. | |
| HANDL, J. - ČAPEK, J. - MAJTNEROVÁ, P. - ROUŠAR, T. Nefrotoxické působení kadmia u lidských proximálních tubulárních buněk. In Czech Chemical Society Symposium Series. Praha: Česká společnost chemická, 2018. |
