Mgr. Katarína Svrčková, Ph.D.
- katarina.svrckova@upce.cz
- 466 037 704
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- Professional profile
- Publications
- Projects
Education and academic qualifications
Rok
2011
Rok
2009
Rok
2015
Job overview
Od (rok)
2017
Do (rok)
současnost
Od (rok)
2016
Do (rok)
2017
Od (rok)
2015
Do (rok)
2015
Study and work stay
Publications
| GONZALEZ, G. - KVASNICA, M. - SVRČKOVÁ, K. - ŠTĚPÁNKOVÁ, Š. - SANTOS, J. - PERINA, M. - JORDA, R. - LOPES, S. - MELO, T. Ring-fused 3 beta-acetoxyandrost-5-enes as novel neuroprotective agents with cholinesterase inhibitory properties Journal of Steroid Biochemistry and Molecular Biology, 2023, vol. 225, no. January, s. 106194. ISSN: 0960-0760. | |
| HOUNGBEDJI, N. - ŠTĚPÁNKOVÁ, Š. - PFLEGR, V. - SVRČKOVÁ, K. - SVARCOVA, M. - VINSOVA, J. - KRATKY, M. Novel Inhibitors of Acetyl- and Butyrylcholinesterase Derived from Benzohydrazides: Synthesis, Evaluation and Docking Study Pharmaceuticals, 2023, vol. 16, no. 2, s. 172. ISSN: 1424-8247. | |
| PFLEGR, V. - ŠTĚPÁNKOVÁ, Š. - SVRČKOVÁ, K. - SVARCOVA, M. - VINSOVA, J. - KRATKY, M. 5-Aryl-1,3,4-oxadiazol-2-amines Decorated with Long Alkyl and Their Analogues: Synthesis, Acetyl- and Butyrylcholinesterase Inhibition and Docking Study Pharmaceuticals, 2022, vol. 15, no. 4, s. 400. ISSN: 1424-8247. | |
| KAŠPAROVÁ, M. - LAŠTOVIČKOVÁ, L. - SVRČKOVÁ, K. Testování biologické aktivity vybraných standardů na enzymy ze skupiny cholinesteras. In Sborník příspěvků: studentská vědecká odborná činnost 2021/2022. Pardubice: Univerzita Pardubice, 2022. s. 91-96 s. ISBN 978-80-7560-434-7. | |
| KRATKY, M. - SVRČKOVÁ, K. - VU, Q. - ŠTĚPÁNKOVÁ, Š. - VINSOVA, J. Hydrazones of 4-(Trifluoromethyl)benzohydrazide as New Inhibitors of Acetyl- and Butyrylcholinesterase Molecules, 2021, vol. 26, no. 4, s. 989. ISSN: 1420-3049. | |
| KOS, J. - STRHARSKY, T. - ŠTĚPÁNKOVÁ, Š. - SVRČKOVÁ, K. - ORAVEC, M. - HOSEK, J. - IMRAMOVSKÝ, A. - JAMPILEK, J. Trimethoxycinnamates and Their Cholinesterase Inhibitory Activity Applied Science - Basel, 2021, vol. 11, no. 10, s. 4691. ISSN: 2076-3417. | |
| KRATKY, M. - VU, Q. - ŠTĚPÁNKOVÁ, Š. - MARUCA, A. - SILVA, T. - AMBROZ, M. - PFLEGR, V. - ROCCA, R. - SVRČKOVÁ, K. - ALCARO, S. - BORGES, F. - VINSOVA, J. Novel propargylamine-based inhibitors of cholinesterases and monoamine oxidases: Synthesis, biological evaluation and docking study Bioorganic Chemistry, 2021, vol. 116, no. November, s. 105301. ISSN: 0045-2068. | |
| MAGAR, P. - PARRAVICINI, O. - ŠTĚPÁNKOVÁ, Š. - SVRČKOVÁ, K. - GARRO, A. - JENDRZEJEWSKA, I. - PAUK, K. - HOSEK, J. - JAMPILEK, J. - ENRIZ, R. - IMRAMOVSKÝ, A. Novel Sulfonamide-Based Carbamates as Selective Inhibitors of BChE International Journal of Molecular Sciences, 2021, vol. 22, no. 17, s. 9447. ISSN: 1661-6596. | |
| KIELCZEWSKA, U. - JORDA, R. - GONZALEZ, G. - MORZYCKI, J. - AJANI, H. - SVRČKOVÁ, K. - ŠTĚPÁNKOVÁ, Š. - WOJTKIELEWICZ, A. The synthesis and cholinesterase inhibitory activities of solasodine analogues with seven-membered F ring Journal of Steroid Biochemistry and Molecular Biology, 2021, vol. 205, no. January, s. 105776. ISSN: 0960-0760. | |
| KRÁTKÝ, M. - ŠTĚPÁNKOVÁ, Š. - KONEČNÁ, K. - SVRČKOVÁ, K. - MAIXNEROVÁ, J. - ŠVARCOVÁ, M. - JANĎOUREK, O. - TREJTNAR, F. - VINŠOVÁ, J. Novel Aminoguanidine Hydrazone Analogues: From Potential Antimicrobial Agents to Potent Cholinesterase Inhibitors Pharmaceuticals, 2021, vol. 14, no. 12, s. 1229. ISSN: 1424-8247. | |
| ŠTĚPÁNKOVÁ, Š. - VOTOČKOVÁ, K. - SVRČKOVÁ, K. USE OF INDOXYL ACETATE AS A SUBSTRATE FOR ACETYLCHOLINESTERASE. In ChemZi. Bratislava: Slovenská chemická spoločnosť pri SAV, 2021. s. 175-175 s. | |
| KRATKY, M. - ŠTĚPÁNKOVÁ, Š. - BRABLIKOVA, M. - SVRČKOVÁ, K. - SVARCOVA, M. - VINSOVA, J. Novel Iodinated Hydrazide-hydrazones and their Analogues as Acetyl- and Butyrylcholinesterase Inhibitors Current Topics in Medicinal Chemistry, 2020, vol. 20, no. 23, s. 2106-2117. ISSN: 1568-0266. | |
| KRATKY, M. - JAKLOVA, K. - ŠTĚPÁNKOVÁ, Š. - SVRČKOVÁ, K. - PFLEGR, V. - VINSOVA, J. N-[3,5-Bis(trifluoromethyl)phenyl]-5-bromo-2-hydroxybenzamide Analogues: Novel Acetyl- and Butyrylcholinesterase inhibitors Current Topics in Medicinal Chemistry, 2020, vol. 20, no. 23, s. 2094-2105. ISSN: 1568-0266. | |
| KRATKY, M. - BARANYAI, Z. - ŠTĚPÁNKOVÁ, Š. - SVRČKOVÁ, K. - SVARCOVA, M. - STOLARIKOVA, J. - HORVATH, L. - BOSZE, S. - VINSOVA, J. N-Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity Molecules, 2020, vol. 25, no. 10, s. 2268. ISSN: 1420-3049. | |
| KRATKY, M. - ŠTĚPÁNKOVÁ, Š. - HOUNGBEDJI, N. - VOSATKA, R. - SVRČKOVÁ, K. - VINSOVA, J. 2-Hydroxy-N-phenylbenzamides and Their Esters Inhibit Acetylcholinesterase and Butyrylcholinesterase Biomolecules, 2019, vol. 9, no. 11, s. "698-1"-"698-16". ISSN: 2218-273X. | |
| KOHELOVA, E. - PERINOVA, R. - MAAFI, N. - KORABECNY, J. - HULCOVA, D. - MARIKOVA, J. - KUCERA, T. - MARTINEZ GONZALEZ, L. - HRABINOVA, M. - SVRČKOVÁ, K. - NOVAKOVA, L. - DE SIMONE, A. - HAVELEK, R. - CAHLIKOVA, L. Derivatives of the beta-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer's Disease Molecules, 2019, vol. 24, no. 7, s. "1307-1"-"1307-18". ISSN: 1420-3049. | |
| BAK, A. - PIZOVA, H. - KOZIK, V. - VORČÁKOVÁ, K. - KOS, J. - TREML, J. - ODEHNALOVA, K. - ORAVEC, M. - IMRAMOVSKÝ, A. - BOBAL, P. - SMOLINSKI, A. - TRÁVNÍČEK, Z. - JAMPILEK, J. SAR-mediated Similarity Assessment of the Property Profile for New, Silicon-Based AChE/BChE Inhibitors International Journal of Molecular Sciences, 2019, vol. 20, no. 21, s. "5385-1"-"5385-29". ISSN: 1422-0067. | |
| KRATKY, M. - ŠTĚPÁNKOVÁ, Š. - VORČÁKOVÁ, K. - VINSOVA, J. Investigation of salicylanilide and 4-chlorophenol-based N-monosubstituted carbamates as potential inhibitors of acetyl- and butyrylcholinesterase Bioorganic Chemistry, 2018, vol. 80, no. October, s. 668-673. ISSN: 0045-2068. | |
| VORČÁKOVÁ, K. - MAJEKOVA, M. - HORÁKOVÁ, E. - DRABINA, P. - SEDLÁK, M. - ŠTĚPÁNKOVÁ, Š. Synthesis and characterization of new inhibitors of cholinesterases based on N-phenylcarbamates: In vitro study of inhibitory effect, type of inhibition, lipophilicity and molecular docking Bioorganic Chemistry, 2018, vol. 78, no. August, s. 280-289. ISSN: 0045-2068. | |
| HORÁKOVÁ, E. - DRABINA, P. - BRŮČKOVÁ, L. - VORČÁKOVÁ, K. - ŠTĚPÁNKOVÁ, Š. - SEDLÁK, M. Synthesis and in vitro evaluation of novel N-cycloalkylcarbamates as potential cholinesterase inhibitors Monatshefte fur Chemie, 2017, vol. 148, no. 12, s. 2143–2153. ISSN: 0026-9247. | |
| KRATKY, M. - ŠTĚPÁNKOVÁ, Š. - VORČÁKOVÁ, K. - NAVRATILOVA, L. - TREJTNAR, F. - STOLARIKOVA, J. - VINSOVA, J. Synthesis of Readily Available Fluorophenylalanine Derivatives and Investigation of Their Biological Activity Bioorganic Chemistry, 2017, vol. 71, no. April, s. 244-256. ISSN: 0045-2068. | |
| HORÁKOVÁ, E. - DRABINA, P. - BROŽ, B. - ŠTĚPÁNKOVÁ, Š. - VORČÁKOVÁ, K. - KRÁLOVEC, K. - HAVELEK, R. - SEDLÁK, M. Synthesis, characterization and in vitro evaluation of substituted N-(2-phenylcyclopropyl)carbamates as acetyl- and butyrylcholinesterase inhibitors Journal of enzyme inhibition and medicinal chemistry, 2016, vol. 31, no. Supp. 3, s. 173-179. ISSN: 1475-6366. | |
| KRÁTKÝ, M. - ŠTĚPÁNKOVÁ, Š. - VORČÁKOVÁ, K. - VINŠOVÁ, J. Synthesis and in vitro evaluation of novel rhodanine derivatives as potential cholinesterase inhibitors Bioorganic Chemistry, 2016, vol. 68, no. October, s. 23-29. ISSN: 0045-2068. | |
| KRÁTKÝ, M. - ŠTĚPÁNKOVÁ, Š. - VORČÁKOVÁ, K. - ŠVARCOVÁ, M. - VINŠOVÁ, J. Novel Cholinesterases Inhibitors Based on O-Aromatic N,N-Disubstituted Carbamates and Thiocarbamates Molecules, 2016, vol. 21, no. 2, s. "191-1"-"191-10". ISSN: 1420-3049. | |
| ŠTĚPÁNKOVÁ, Š. - VORČÁKOVÁ, K. Cholinesterase based biosensors Journal of enzyme inhibition and medicinal chemistry, 2016, vol. 31, no. Suppl. 3, s. 180-193. ISSN: 1475-6366. | |
| VORČÁKOVÁ, K. - ŠTĚPÁNKOVÁ, Š. - SEDLÁK, M. - VYTŘAS, K. Electrochemical Sensors for the Estimation of the Inhibitory Effect of Phenylcarbamates to Cholinesterase Chemosensors, 2015, vol. 3, no. 4, s. 274-283. ISSN: 2227-9040. | |
| VORČÁKOVÁ, K. - ŠTĚPÁNKOVÁ, Š. - IMRAMOVSKÝ, A. Benzothiazoles as effective inhibitors of cholinesterases: Kinetics and mechanism of inhibition Scientific Papers of the University of Pardubice, Series A, Faculty of Chemical Technology, 2015, vol. 21, no. září, s. 31-43. ISSN: 1211-5541. | |
| KRATKÝ, M. - ŠTĚPÁNKOVÁ, Š. - VORČÁKOVÁ, K. - VINŠOVÁ, J. Salicylanilide diethyl phosphates as cholinesterases inhibitors Bioorganic Chemistry, 2015, vol. 58, no. February, s. 48-52. ISSN: 0045-2068. | |
| VORČÁKOVÁ, K. - ŠTĚPÁNKOVÁ, Š. - KRÁTKY, M. - VINŠOVÁ, J. Application of Human Cholinesterase in Determination of Inhibitory Effect of Salicylanilide diethyl phosphates. In 4th International Miniconference of PhD Students: When Biochemistry Meets Pharmacology and Toxicology. Bratislava: Ústav experimentálnej farmakológie a toxikológie SAV, 2015. s. 17-20 s. ISBN 978-80-971042-5-2. | |
| VINSOVA, J. - KRATKY, M. - KOMLOOVA, M. - DADAPEER, E. - ŠTĚPÁNKOVÁ, Š. - VORČÁKOVÁ, K. - STOLARIKOVA, J. Diethyl 2-(Phenylcarbamoyl)phenyl Phosphorothioates: Synthesis, Antimycobacterial Activity and Cholinesterase Inhibition Molecules, 2014, vol. 19, no. 6, s. 7152-7168. ISSN: 1420-3049. | |
| ŠTĚPÁNKOVÁ, Š. - VORČÁKOVÁ, K. Inhibitory effect of carbamates in two types of cholinesterases Scientific Papers of the University of Pardubice, Series A, Faculty of Chemical Technology, 2013, vol. 19, no. prosinec, s. 49-56. ISSN: 1211-5541. | |
| IMRAMOVSKÝ, A. - PEJCHAL, V. - ŠTĚPÁNKOVÁ, Š. - VORČÁKOVÁ, K. - JAMPÍLEK, J. - VANČO, J. - ŠIMŮNEK, P. - KRÁLOVEC, K. - BRŮČKOVÁ, L. - MANDÍKOVÁ, J. - TREJTNAR, F. Synthesis and in vitro evaluation of new derivatives of 2-substituted-6-fluorobenzo[d]thiazoles as cholinesterase inhibitors Bioorganic & Medicinal Chemistry, 2013, vol. 21, no. 7, s. 1735-1748. ISSN: 0968-0896. | |
| VORČÁKOVÁ, K. - ŠTĚPÁNKOVÁ, Š. - IMRAMOVSKÝ, A. Stanovenie anticholinesterasovej aktivity vybraných benzothiazolov. In Študentská vedecká konferencia PriF UK 2012. Bratislava: Univerzita Komenského v Bratislave, 2012. s. 1063-1067 s. ISBN 978-80-223-3213-2. | |
| VORČÁKOVÁ, K. - ŠTĚPÁNKOVÁ, Š. - ZORIČ, P. - SEDLÁK, M. - METELKA, R. - VYTŘAS, K. Application of Electrochemical Sensors for Determination of Anticholinesterase Activity and Immobilization of Enzyme. In Sensing in Electroanalysis Vol. 7. Pardubice: Univerzita Pardubice, 2012. s. 409-422 s. ISBN 978-80-7395-563-2. |
Projects
Modern analytical, molecular biological, microbiological and cytological methods for analysis of biological samples
01.01.20 - 31.12.20
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
01.01.20 - 31.12.20
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
The use of modern analytical, molecular biological, microbiological and cytological methods for analysis of biological samples
01.01.19 - 31.12.19
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
01.01.19 - 31.12.19
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
The use of analytical, molecular biological, microbiological and cytological methods for analysis of biological samples
01.01.16 - 31.12.16
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator
01.01.16 - 31.12.16
Programme: Student Grant Competition
Funded by:
Position on the project: Co-Investigator