Immobilized Enantioselective Catalysts
Provider: Grantová agentura ČR
Programme: Standardní projekty (řešení od 1.1.2014)
Implementation period: 01.01.14 - 31.12.16
Workplace:
Fakulta chemicko-technologická - Ústav organické chemie a technologie
Investigator: Sedlák Miloš
Description:
The objective of the project is preparation and characterization of new, highly efficient, recoverable enantioselective catalysts. The suggestedsystems are based on chiral, optically pure imidazolidine-4-ones, their new derivatives and their complexes with transition metals and on theknown homogeneous catalysts (derivatives of proline, quinine, cyclohexan1,2-diamine,1,2-diphenylethan-1,2-diamine), which will beimmobilized on a selected polymers (substituted polyethylene gylcols, cross-linked styrene copolymers) and magnetic micro- or nanoparticlesof (Fe3O4@SiO2).The prepared catalysts will be tested in the reactions with high potential for industrial applications, such as Henry reaction, Michael addition reaction and aldolization.
The objective of the project is preparation and characterization of new, highly efficient, recoverable enantioselective catalysts. The suggestedsystems are based on chiral, optically pure imidazolidine-4-ones, their new derivatives and their complexes with transition metals and on theknown homogeneous catalysts (derivatives of proline, quinine, cyclohexan1,2-diamine,1,2-diphenylethan-1,2-diamine), which will beimmobilized on a selected polymers (substituted polyethylene gylcols, cross-linked styrene copolymers) and magnetic micro- or nanoparticlesof (Fe3O4@SiO2).The prepared catalysts will be tested in the reactions with high potential for industrial applications, such as Henry reaction, Michael addition reaction and aldolization.
