Skip to main content

Login for students

Login for employees

Publication detail

Targeted Conjugates of Prednisolone Based on Polypseudorotaxanes
Authors: Sedlák Miloš
Year: 2012
Type of publication: ostatní - přednáška nebo poster
Page from-to: nestránkováno
Titles:
Language Name Abstract Keywords
eng Targeted Conjugates of Prednisolone Based on Polypseudorotaxanes The pH-sensitive and esterase-sensitive conjugates of prednisolone was prepared as a new targeted delivery systems. The synthesized conjugates form polypseudorotaxanes with alpha-cyclodextrin were characterized by NMR spectra, powder X-ray diffraction patterns and by STM microscopy. The rate of acid-catalysed of and esterase catalyzed hydrolysis of the conjugate was studied under in vitro conditions in model media. Conjugates; Prednisolone; Polypseudorotaxanes