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Double Displacement Type of Mechanism in the Transformation of Isothiouronium Salts

Authors: Váňa Jiří | Sedlák Miloš | Roithová Jana | Škríba Anton | Jašík Juraj | Hanusek Jiří

Year: 2012

Type of publication: ostatní - přednáška nebo poster

Page from-to: nestránkováno

Titles:

Language	Name	Abstract	Keywords
eng	Double Displacement Type of Mechanism in the Transformation of Isothiouronium Salts	We proposed mechanism for the transformation of substituted S-(3-oxo-1,3-dihydro-2-benzofuran-1-yl)- N,N'-dimethyl isothiouronium salts to the corresponding 1,3-dimethyl-1-(3-oxo-1,3-dihydro-2-benzofuran-1-yl)thioureas. Three possible limiting mechanisms – SN1, SN2 or double displacement1 - come into consideration. Infrared multiphoton dissociation spectroscopy (IRMPD)2 indicates thiazetidine skeleton to be the reaction intermediate in the gas phase. This observation together with trapping experiments and behaviour of relative compounds suggest the idea of the double displacement mechanism as the most probable reaction mechanism explanation.	Displacement; Mechanism; Transformation; Isothiouronium Salts