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MAGNETIC BEAD-BASED IMMUNOCAPTURE OF CLINICAL BIOMARKERS IN MICROFLUIDIC DEVICES: FROM PEPTIDES TO WHOLE CELLS
Authors: Svobodová Zuzana | Jankovičová Barbora | Srbová Jana | Bílková Zuzana
Year: 2014
Type of publication: ostatní - přednáška nebo poster
Page from-to: nestránkováno
Titles:
Language Name Abstract Keywords
eng MAGNETIC BEAD-BASED IMMUNOCAPTURE OF CLINICAL BIOMARKERS IN MICROFLUIDIC DEVICES: FROM PEPTIDES TO WHOLE CELLS Detection of specific clinical biomarkers occurring mostly in low concentrations in body fluids is highly challenging, therefore special techniques for their isolation and preconcentration from complex biological samples is required. Immunocapture of two diverse biomarkers such as peptides (amyloid β) and/or cells (circulating tumour cells) using magnetic immunosorbent (MIS) was performed inside two microfluidic devices tailored specially for each biomarker. Results achieved on development of MISs for microfluidic purposes as well as its evaluation inside the microfluidic devices in past 6 years are presented in here. immunocapture, magnetic beads, microfluidic, peptide, cell