Publication detail

STUDY OF MECHANISM OF ACETAMINOPHEN TOXICITY

Year: 2016

Type of publication: ostatní - přednáška nebo poster

Name of source: Studentská vědecká odborná činnost 2015/2016 : sborník příspěvků

Publisher name: Univerzita Pardubice

Place: Pardubice

Page from-to: 15-20

Titles:

Language	Name	Abstract	Keywords
eng	STUDY OF MECHANISM OF ACETAMINOPHEN TOXICITY	Acetaminophen (APAP) belongs among mostly used antipyretics and analgesics. It is a safe drug at therapeutic doses. However, after overdose, it can cause cell impairment that may lead to acute liver and/or kidney failure. Although the toxicity has been studied widely, its entire mechanism remains unknown. To introduce specific treatment of APAP overdose, new approaches have been requested but no alternative to N-acetylcysteine treatment rather have been found.	Acetaminophen; toxicity

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