Publication detail

Interaction between the API and excipients in solid state dosage form prepared by direct compression method

Authors: Romanová Jana | Svoboda Roman | Komersová Alena | Pekárek T

Year: 2018

Type of publication: ostatní - článek ve sborníku

Name of source: 13th International Conference on Solid State Chemistry : book of abstracts

Publisher name: Univerzita Pardubice

Place: Pardubice

Page from-to: 168-168

Titles:

Language	Name	Abstract	Keywords
eng	Interaction between the API and excipients in solid state dosage form prepared by direct compression method	the objective of this study is to clarify the possible interaction between SA and excipients. teh mixture of SA and excipients was examined over the time by using differential scanning calorimetry, infrared spectrocopy and Raman mapping. presence of the interaction was confirmed based on the occurence of eutectic melting peak on the calorimetric signal. true nature of the interaction will be discussed based on the spectroscopic data.	Interaction; API; excipient; salicylic acid; Kollidon; sustained release

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