Publication detail

Chemical Interactions in Solid State: Changes in Behaviour of Matrix Tablets Due to the Chemical Interactions of Individual Components

Authors: Romanová Jana | Komersová Alena | Svoboda Roman | Pekárek T

Year: 2019

Type of publication: ostatní - článek ve sborníku

Name of source: 7th International Conference on Chemical Technology : book of abstracts

Publisher name: Česká společnost průmyslové chemie

Place: Praha

Page from-to: PH8-PH8

Titles:

Language	Name	Abstract	Keywords
eng	Chemical Interactions in Solid State: Changes in Behaviour of Matrix Tablets Due to the Chemical Interactions of Individual Components	The main part of this study was focused on the comparison of the physical binary mixtures of SA and Kollidon® SR with compressed mixtures of the same components. The binary mixtures of SA and Kollidon® SR (physical, compressed) were prepared in different ratios. Based on the results from differential scanning calorimetry, we identified the ratio where the interaction was observed the most. The type of interaction was estimated by spectral methods. The same type of interactions as in the compressed binary mixtures was observed also in tablets.	chemical interaction; matrix tablet; Kollidon

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