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Ultrathin TiO2 ALD Coatings Enhance Properties of Biomaterials Used in Implantology

Authors: Báčová Jana | Čapek Jan | Baishya Kaushik | Zazpe Raul | Sopha Hanna Ingrid | Sepulveda Sepulveda Lina Marcela | Roušar Tomáš | Macák Jan

Year: 2024

Type of publication: ostatní - přednáška nebo poster

Page from-to: nestránkováno

Titles:

Language	Name	Abstract	Keywords
eng	Ultrathin TiO2 ALD Coatings Enhance Properties of Biomaterials Used in Implantology	Various TiO2 nanostructured surfaces are generally recognized as excellent biocompatible materials. Anodic TiO2 nanotube (TNT) layers have emerged as extremely suitable and effective substrates for surface modification of various materials used in biomedical applications, especially TiAlV alloy. Recently, we compared the biological effect of ultrathin TiO2 coatings, achieved by various numbers of Atomic Layer Deposition (ALD) cycles, on planar and nanotubular surfaces. We demonstrated that ultrathin TiO2 ALD coatings on TNT layers enhanced cell adhesion, growth, and proliferation [1]. Furthermore, we found that 1 cycle of TiO2 ALD coating shaded the impurities of F- and V-based species in tested TiAlV alloys while preserving the original structure and morphology. ALD modification makes tested materials suitable candidates for bone and dental implants [2]. For the first time, single-cell adhesion to modified TNT layers using the ALD method was studied by bio-Atomic Force Microscopy [3]. References: 1. Motola, M., Capek, J. et al., ACS Applied Bio Materials (2020). 2. Capek, J., Sepúlveda, M. et al., ACS Applied Materials & Interfaces (2024). 3. Baishya, K., Vrchovecka, K. et al., Applied Surface Science Advances (2023).	nanotubes; osteoblasts; atomic layer deposition