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Clusters of magnetic nanoparticles as contrast agents for MRI: The effect of aggregation on T2 relaxivity
Autoři: Dědourková Tereza | Kaman Ondřej | Veverka Pavel | Koktan Jakub | Veverka Miroslav | Kuličková Jarmila | Jirák Zdeněk | Herynek Vít
Rok: 2015
Druh publikace: ostatní - článek ve sborníku
Název zdroje: INTERMAG 2015 - IEEE International Magnetics Conference: Proceedings
Název nakladatele: IEEE (Institute of Electrical and Electronics Engineers)
Místo vydání: New York
Strana od-do: "BI-07-1"-"BI-07-1"
Tituly:
Jazyk Název Abstrakt Klíčová slova
eng Clusters of magnetic nanoparticles as contrast agents for MRI: The effect of aggregation on T2 relaxivity The effect of aggregation of magnetic nanoparticles on the transverse relaxivity (r2) is analyzed with respect to the size of clusters. The nanoparticles employed are based on La0.75Sr0.25MnO3 ferromagnetic phase with the mean size of crystallites dXRD = 26 encapsulated by silica shell. The silica coating provides colloidally stable particles whose magnetic cores are mostly composed of compact clusters of manganite crystallites. The product has been subjected to repeated differential centrifugation and several size fractions are isolated. The highest r2 values are clearly observed for midsized clusters and the temperature dependence of r2 resembles the evolution of magnetization with temperature. Supplemental samples with different thicknesses of the silica shell are also synthetized and thoroughly analyzed. Contrast Agents;Magnetic Nanoparticles;Magnetic Resonance Imaging;Manganites;Transverse Relaxivity