Publikace detail

UHPLC/MS/MS charakterizace of anthelmintik a jejich metabolitů

Autoři: Jedličková Veronika | Jirásko Robert | Holčapek Michal | Skálová Lenka

Rok: 2010

Druh publikace: ostatní - přednáška nebo poster

Strana od-do: nestránkováno

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
cze	UHPLC/MS/MS charakterizace of anthelmintik a jejich metabolitů	In our study, selected parasites are cultivated in flasks with a medium enriched by praziquantel (or ivermectin) and subsequently analyzed using UHPLC/MS/MS with the electrospray ionization. Both ESI polarity modes are used to obtain complementary information. The emphasis is given on the right calibration of the mass scale to achieve the high mass accuracy, which results in the elemental composition determination of ions observed in full-scan and tandem mass spectra. Moreover, advanced software tools are used for the prediction and identification of eventual metabolites.	UHPLC/MS/MS; anthelmintikum; hmotnostní spektrometrie

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