Publikace detail

In vitro studies of anthelmintik drugs

Rok: 2011

Druh publikace: ostatní - přednáška nebo poster

Strana od-do: nestránkováno

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
eng	In vitro studies of anthelmintik drugs	In this work, in vitro studies of anthelminthic drug ivermectin were performed. Rat hepatic cells and rat or parasitic mitochondrial fractions were used as biological models for incubations with the drug. The solid-phase extraction method was optimized for incubation mixtures. Extracted samples were subsequently analysed by UHPLC/MS/MS with the emphasis to detect and identify phase I and II metabolites of ivermectin.	ivermectin;UHPLC/MS/MS;drug metabolites

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