Publikace detail

In vitro and in vivo studies of praziquantel and its metabolites using UHPLC/MS/MS

Autoři: Jedličková Veronika | Jirásko Robert | Holčapek Michal | Vokřál Ivan | Skálová Lenka

Rok: 2011

Druh publikace: ostatní - přednáška nebo poster

Strana od-do: nestránkováno

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
eng	In vitro and in vivo studies of praziquantel and its metabolites using UHPLC/MS/MS	In this work, in vitro and in vivo studies of anthelminthic drug praziquantel were performed. The solid-phase extraction method was optimized for incubation mixtures. Extracted samples were subsequently analysed by UHPLC/MS/MS with the emphasis to detect and identify phase I and II metabolites of praziquantel.	praziquantel;drug metabolites;UHPLC/MS/MS

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