Publikace detail

Targeted Conjugates of Prednisolone Based on Polypseudorotaxanes

Rok: 2012

Druh publikace: ostatní - přednáška nebo poster

Strana od-do: nestránkováno

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
eng	Targeted Conjugates of Prednisolone Based on Polypseudorotaxanes	The pH-sensitive and esterase-sensitive conjugates of prednisolone was prepared as a new targeted delivery systems. The synthesized conjugates form polypseudorotaxanes with alpha-cyclodextrin were characterized by NMR spectra, powder X-ray diffraction patterns and by STM microscopy. The rate of acid-catalysed of and esterase catalyzed hydrolysis of the conjugate was studied under in vitro conditions in model media.	Conjugates; Prednisolone; Polypseudorotaxanes

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