Univerzita PardubiceFakulta chemicko- technologická

Univerzita Pardubice

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Publikace detail

pH Switchable fluorophores based on 5-(2-hydroxyphenyl)-1,3-thiazol-4-oles

Autoři: Kammel Richard | Hanusek Jiří

Rok: 2014

Druh publikace: ostatní - přednáška nebo poster

Strana od-do: nestránkováno

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
eng	pH Switchable fluorophores based on 5-(2-hydroxyphenyl)-1,3-thiazol-4-oles	1,3-Thiazol-4-oles are good fluorophores4 in solutions and sometimes also in solid state. It is also known that the presence of some ionizable groups (OH, NH2 etc.) can significantly affect the shift of their UV absorption/fluorescence band. For preparation of 1,3-thiazol-4-oles we used aromatic thioamides as a starting material. We have prepared a new set of substituted 5-(2-hydroxyphenyl)-1,3-thiazol-4-oles (1a-g) and studied their spectral properties under various conditions. The title compounds were prepared from 3-bromocoumaran-2-one and aromatic thioamides in acetonitrile. After one hour hydrobromides of substituted 1,3-thiazol-4-oles have been isolated which have been subsequently converted to 1a-g using suitable base (aq. NH3)	fluorophor; 5-(2-hydroxyphenyl)-1,3-thiazol-4-oles, pH-dependence