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Electrochemical behavior and voltammetric determination of folates folic acid and leucovorin and antifolate methotrexate using bare boron-doped diamind electrode

Autoři: Šelešovská Renáta | Bandžuchová Lenka | Chýlková Jaromíra

Rok: 2014

Druh publikace: ostatní - článek ve sborníku

Název zdroje: 15th International Conference on Electroanalysis

Název nakladatele: Malmö University

Místo vydání: Malmö

Strana od-do: 214

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
eng	Electrochemical behavior and voltammetric determination of folates folic acid and leucovorin and antifolate methotrexate using bare boron-doped diamind electrode	The possibility of application of bare boron-doped diamond electrode (BDDE) in voltammetric analysis of the folates folic acid and leucovorin and antifolate methotrexate has been investigated. Cyclic voltammetry and direct current voltammetry has been used for study of its voltammetric behavior. Differential pulse voltammetry has been applied for development of sensitive methods of determination for tested electroactive compounds. Various statistical parameters, e.g., relative standard deviations of repeated measurements or limits of detection, were calculated. The proposed methods were successfully applied for analysis of real samples of vitamin products and drugs.	Boron-doped diamond electrode; Voltammetric analysis; Folic acid; Leucovorin; Methotrexate

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