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Bead-based immunosensor for early stage diagnosis of ovarian cancer
Autoři: Čadková Michaela | Dvořáková Veronika | Metelka Radovan | Bílková Zuzana | Korecká Lucie
Rok: 2014
Druh publikace: ostatní - přednáška nebo poster
Strana od-do: nestránkováno
Tituly:
Jazyk Název Abstrakt Klíčová slova
eng Bead-based immunosensor for early stage diagnosis of ovarian cancer Ovarian cancer is the fifth leading cause of all cancer related mortality among women. Since ovarian cancer is the asymptomatic at early stages, most patients present with advanced disease when diagnosed. Human epididymal protein-4 (HE4) is nowadays of great importance as new promising biomarker of ovarian cancer. HE4 is more specific than currently used biomarker CA125 and it´s level in human blood correlates with the stage of disease. The aim of this work is to develop highly sensitive and selective electrochemical immunomagnetic sensors for early detection of HE4. immunosensor; ovarian cancer; HE4; magnetic particles