Publikace detail

Analysis of tight junction proteins in human epidermis by confocal microscope

Autoři: Svoboda Marek | Vojtěch Pavlík | Marta Hlobilová | Tomáš Muthný

Rok: 2015

Druh publikace: ostatní - přednáška nebo poster

Strana od-do: nestránkováno

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
eng	Analysis of tight junction proteins in human epidermis by confocal microscope	Epidermal tight junctions (TJ) represents crucial regulatory element of epidermal homeostasis. Since the skin creates barrier to external environment, epidermal TJs are exposed to various factors that may deregulate them. Deregulation may occur not only as altered quantity of TJ proteins but also as altered localization pattern. Therefore, human skin samples of young and aged individuals were analyzed by confocal laser scanning microscopy (CLSM). CLSM has enabled us to detect changes in localization of one of the main TJ protein, claudin-1 in photoaged skin sample.	confocal microscopy, claudin-1, epidermis, tight-junctions

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