Publikace detail

Detection of Mycoplasma hominis in amniotic fluid of pregnant women by real-time PCR

Autoři: Vydržalová Markéta | Lysková Petra | Kroupa Tomáš | Mazurová Jaroslava

Rok: 2008

Druh publikace: článek ve sborníku

Název zdroje: Clinical Microbiology and Infection

Název nakladatele: Blackwell Publishing Ltd

Místo vydání: Oxford

Strana od-do: S581-S582

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
cze	Detekce Mycoplasma hominis v plodové vodě těhotných žen metodou real-time PCR	Infekce matky během těhotenství hraje velkou roli při postižení plodu a spontánních potratech. Jednou z nějčastěji se vyskytujících bakterií při intrauterinních infekcích je Mycoplasma hominis. Naše studie hodnotila vztah mezi výskytem Mycoplasma hominis v plodové vodě, průběhem těhotenství a zdravotním stavem novorozence.	Mycoplasma hominis,real-time PCR,plodová voda
eng	Detection of Mycoplasma hominis in amniotic fluid of pregnant women by real-time PCR	Objectives: Maternal infection has long been known to play a major role in perinatal morbidity and mortality and suspected to be a cause of spontaneous abortion. Intrauterine infection may be largely responsible for preterm delivery. The most common microorganism involved in intrauterine infections is Mycoplasma hominis. Mycoplasma hominis is commonly isolated microorganism from the female genital tract. It has been linked to pelvic inflammatory diseases such as salpingitis, endometritis, bacterial vaginosis and infertility. The transmition from the mother to the developing fetus can be in utero or at delivery. The relationship between detection of Mycoplasma hominis in mid-trimester amniotic fluid and subsequent pregnancy outcome was investigated. Data collected included indication for amniocentesis, gestational age at amniocentesis, gestational age at delivery, pregnancy outcome and low birth weight of infants. Method: The amniotic fluids of 202 women who underwent a transabdominal amniocentesis at weeks 15 - 22 of pregnancy were tested for Mycoplasma hominis by real-time PCR. Results: Mycoplasma hominis were identified in 51 (25.2 %) samples of the amniotic fluid. A total of two (28.6 %) infants, positive for Mycoplasma hominis, had the birth weight below 2500g. Ten of the women had preterm delivery and one of them (10 %) was positive for Mycoplasma hominis. Conclusion: In this study has not been found statistical correlation between Mycoplasma hominis and low birth weight and preterm delivery. Despite the detection of Mycoplasma hominis in samples of pregnant women should be considered. Real-time PCR is suitable for diagnostic of this microorganism in samples of amniotic fluid.	Mycoplasma hominis,real-time PCR,amniotic fluid

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