Publikace detail

A liquid chromatographer's introduction to mass spectrometry

Autoři: Holčapek Michal

Rok: 2009

Druh publikace: elektronická a audiovizuální tvorba

Název zdroje: Separation Science

Název nakladatele: neuveden

Strana od-do: nestránkováno

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
cze
eng	A liquid chromatographer's introduction to mass spectrometry	Mass spectrometry is used for the structural elucidation or confirmation of organic, bioorganic and organometallic compounds and for quantitative analysis in environmental, pharmaceutical, forensic, food/feed, and other sciences. The first step in the measurement is the conversion of neutral molecules to charged species (i.e. ions), which are then separated according to their mass-to-charge (m/z) ratio in a mass analyzer. The relative abundances of individual m/z values are recorded by a suitable detector to produce what is known as a mass spectrum. Mass spectrometry can be coupled to both gas-phase and liquid-phase separation techniques, enabling the structural analysis of complex mixtures after their chromatographic separation without time consuming off-line isolation.	mass spectrometry;liquid chromatography

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